Presentation 2006-06-23
Simulation of muscle metabolism with a mathematical model for analyses of muscle oxygen measurements using near-infrared spectroscopy
Khai Jun KEK, Satoko YONEYAMA, Takahiro MIYAKAWA, Nobuki KUDO, Katsuyuki YAMAMOTO,
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Abstract(in English) Near-infrared spectroscopy (NIRS) is a technique for noninvasive measurement of muscle oxygenation. However, analyses of the dynamic changes in metabolism based only on NIRS measurements are difficult because the changes in muscle oxygenation could be affected by different factors of the complex metabolic system. Therefore, we constructed a model of muscle metabolism to identify the mechanisms responsible for experimental observation of NIRS measurements. Simulations that were performed with the model sufficiently reproduced the characteristic temporal changes of NIRS measurements. The results demonstrate the usefulness of the model for elucidation of the relationship between muscle metabolism and NIRS measurements.
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Keyword(in English) Near-infrared spectroscopy / muscle metabolism / mathematical model / simulation
Paper # MBE2006-28
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Conference Information
Committee MBE
Conference Date 2006/6/16(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language ENG
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Simulation of muscle metabolism with a mathematical model for analyses of muscle oxygen measurements using near-infrared spectroscopy
Sub Title (in English)
Keyword(1) Near-infrared spectroscopy
Keyword(2) muscle metabolism
Keyword(3) mathematical model
Keyword(4) simulation
1st Author's Name Khai Jun KEK
1st Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University()
2nd Author's Name Satoko YONEYAMA
2nd Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
3rd Author's Name Takahiro MIYAKAWA
3rd Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
4th Author's Name Nobuki KUDO
4th Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
5th Author's Name Katsuyuki YAMAMOTO
5th Author's Affiliation Graduate School of Information Science and Technology, Hokkaido University
Date 2006-06-23
Paper # MBE2006-28
Volume (vol) vol.106
Number (no) 127
Page pp.pp.-
#Pages 4
Date of Issue