Presentation | 2006-03-15 BCM-type synaptic plasticity using the threshold as linear summation of calcium concentration Hiroki KURASHIGE, Yutaka SAKAI, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | So far, changes in synaptic strength have been modeled as assuming that decided based on an absolute level of the calcium concentration. However, it has been pointed out not to be able to reproduce the properties of the spike-timing-dependent plasticity (STDP) by such a model. In this study, we present a model for synaptic plasticity based on the difference between the calcium inflow caused by pairing of presynaptic firing and postsynaptic firing and the linear summation of the calcium inflows caused by presynaptic firing and postsynaptic firing, and examine it by simulation experiment using NEURON simulator. It is shown that the timing property and the dependence on initial synaptic strength of STDP are reproduced using this model. In addition, we show that it is able to be important for the dependence on initial synaptic strength that NMDA conductance has some value even when AMPA conductance has the value of almost 0. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | STDP / calcium concentration / BCM rule / NMDA channel |
Paper # | NC2005-113 |
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Committee | NC |
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Conference Date | 2006/3/8(1days) |
Place (in Japanese) | (See Japanese page) |
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Registration To | Neurocomputing (NC) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | BCM-type synaptic plasticity using the threshold as linear summation of calcium concentration |
Sub Title (in English) | |
Keyword(1) | STDP |
Keyword(2) | calcium concentration |
Keyword(3) | BCM rule |
Keyword(4) | NMDA channel |
1st Author's Name | Hiroki KURASHIGE |
1st Author's Affiliation | Graduate school of Engineering, Tamagawa University() |
2nd Author's Name | Yutaka SAKAI |
2nd Author's Affiliation | Faculty of Engineering, Tamagawa University |
Date | 2006-03-15 |
Paper # | NC2005-113 |
Volume (vol) | vol.105 |
Number (no) | 657 |
Page | pp.pp.- |
#Pages | 6 |
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