| Presentation | 2006-01-28 Effect of ELF electrostimulation on NO-generating ability of macrophage Yuji KURACHI, Toshiyuki SHIMOOKA, Muneyoshi KAGAWA, Koichi SHIMIZU, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We have reported the possible effect of ELF electrostimulation on the reactive oxygen generation of a macrophage. In this study, we examined the effect of the electrostimulation on the NO that was a kind of the same radical generation of a macrophage in vitro. The NO generation was suppressed by the electrostimulation (50Hz, 35μA/cm^2, 16h) with statistical significance. As the mechanism of this effect, the iNOS generation was also examined. It was suppressed in the same ratio as the NO generation. The dose-response of these effects was analyzed, and the threshold was found between 0.35μA/cm^2 and 3.5μA/cm^2. The results of this study suggest that the NO generation can be suppressed by electrostimulation though the mechanism of iNOS suppression. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | NO / iNOS / ELF electric field / Peritoneal Exudate Macrophage |
| Paper # | MBE2005-127 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2006/1/21(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Effect of ELF electrostimulation on NO-generating ability of macrophage |
| Sub Title (in English) | |
| Keyword(1) | NO |
| Keyword(2) | iNOS |
| Keyword(3) | ELF electric field |
| Keyword(4) | Peritoneal Exudate Macrophage |
| 1st Author's Name | Yuji KURACHI |
| 1st Author's Affiliation | Graduate School of Information Science and Technology, Hokkaido University() |
| 2nd Author's Name | Toshiyuki SHIMOOKA |
| 2nd Author's Affiliation | Graduate School of Information Science and Technology, Hokkaido University |
| 3rd Author's Name | Muneyoshi KAGAWA |
| 3rd Author's Affiliation | Graduate School of Information Science and Technology, Hokkaido University |
| 4th Author's Name | Koichi SHIMIZU |
| 4th Author's Affiliation | Graduate School of Information Science and Technology, Hokkaido University |
| Date | 2006-01-28 |
| Paper # | MBE2005-127 |
| Volume (vol) | vol.105 |
| Number (no) | 578 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |