Presentation 2005/10/10
A Model for Calcium System and Repetitive Firing in Motoneurons
Katsumi WADA,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) The author developed a novel motoneuron model based on a recent quantitative data on the calcium-dependent potassium conductance (AHP conductance), and examined whether steady-state frequency-current relations (f-I curve) could be accounted for by the model. The model includes calcium conductances and intracellular calcium systems (i.e., diffusion, buffering and extrusion) as well as sodium and potassium conductances. An f-I curve consisting of three quasi-line segments was reproduced by the model. The behavior of the AHP conductance in the secondary range was the same as in the primary range although its amplitude was smaller. The average activation level of the AHP conductance varied with the firing rate and its maximum value was attained around at the transition point to the secondary range. The reason for the abrupt bends of the f-I curve was discussed based on the effects of the elimination of the AHP conductance on the f-I curve.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) motoneuron / f-I curve / Ca-system / AHP
Paper # NC2005-40
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Conference Information
Committee NC
Conference Date 2005/10/10(1days)
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Paper Information
Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) A Model for Calcium System and Repetitive Firing in Motoneurons
Sub Title (in English)
Keyword(1) motoneuron
Keyword(2) f-I curve
Keyword(3) Ca-system
Keyword(4) AHP
1st Author's Name Katsumi WADA
1st Author's Affiliation Graduate School of Information System, University of Electro-Communications()
Date 2005/10/10
Paper # NC2005-40
Volume (vol) vol.105
Number (no) 341
Page pp.pp.-
#Pages 8
Date of Issue