| Presentation | 2002/8/16 Development of Fiber-Optic Sensor System for Metabolic Reactions of Enzyme of Cytochrome-P450 Isao YAMAKAWA, Issei SASAKI, Tomoki WATANABE, Yuuta SAITOH, Atsushi USUI, Asako TAKAHASHI, Akio KAZUSAKA, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | All kind of living things has an effective life guard system against toxicants by inducing Gytochrome P450 (GYP) for metabolizing such chemical species. Some molecular types of super family of GYP are induced by environmental pollutant and some are strongly related to cancer development. In order to contribute to environmental assessment of pollutants and cancer diagnostics based on the in vivo sensing of CYP, the authors have intensively developed an optical-bio sensing system by using optical fiber sensor, that effectively detects fluorescent from molecular produced by a particular type of CYP. This paper reports about the recent development on the fiber-optic CYP detection technique, by using rat liver and benzopyrene as a carcinogen and 2,3,7,8-TCDF as environmental pollutant. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | fiber-optic sensor / cytochrome P450 / cancer development / environmental assessment |
| Paper # | OFT2002-35 |
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| Conference Information | |
| Committee | OFT |
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| Conference Date | 2002/8/16(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | |
| Vice Chair | |
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| Paper Information | |
| Registration To | Optical Fiber Technology (OFT) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Development of Fiber-Optic Sensor System for Metabolic Reactions of Enzyme of Cytochrome-P450 |
| Sub Title (in English) | |
| Keyword(1) | fiber-optic sensor |
| Keyword(2) | cytochrome P450 |
| Keyword(3) | cancer development |
| Keyword(4) | environmental assessment |
| 1st Author's Name | Isao YAMAKAWA |
| 1st Author's Affiliation | Hokkaido Institute of Technology:R&D Lab. for Optical Fiber Applications, Advanced Technology Inc.() |
| 2nd Author's Name | Issei SASAKI |
| 2nd Author's Affiliation | Hokkaido Institute of Technology:R&D Lab. for Optical Fiber Applications, Advanced Technology Inc. |
| 3rd Author's Name | Tomoki WATANABE |
| 3rd Author's Affiliation | Hokkaido College of Pharmacy |
| 4th Author's Name | Yuuta SAITOH |
| 4th Author's Affiliation | Hokkaido Institute of Technology |
| 5th Author's Name | Atsushi USUI |
| 5th Author's Affiliation | Hokkaido Institute of Technology |
| 6th Author's Name | Asako TAKAHASHI |
| 6th Author's Affiliation | Hokkaido Institute of Technology |
| 7th Author's Name | Akio KAZUSAKA |
| 7th Author's Affiliation | Grad. School of Vet. Med., Hokkaido University |
| Date | 2002/8/16 |
| Paper # | OFT2002-35 |
| Volume (vol) | vol.102 |
| Number (no) | 270 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |