| Presentation | 1999/10/27 Theoretical study on the mechanisms of spontaneous wave breakup of spiral wave in cardiac fibrillation Takashi Ashihara, Tsunetoyo Namba, Tohru Suzuki, Takanori Ikeda, Makoto Ito, Masahiko Kinoshita, Kazuo Nakazawa, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Recent studies have suggested that chaotic tachyarrhythmia (cardiac fibrillation) is based on a "spiral wave" with the spontaneous wave breakup (SWB). However, the details of the related mechanisms have still not been clarified. In this study, we employed a one-dimensional Luo-Rudy model to simulate the electrophysiological characteristics of the spiral arm. The influence of the spiral core potential altered the electrophysiological characteristics of the arm. Therefore, alternating action potential duration (APD) along the arm near the core converged, and at the same time, that far from the core diverged. It was highly probable that the first SWB point was in the APD divergent zone beside the APD convergent zone. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | tachyarrhythmia / spiral wave / fibrillation / spontaneous wave breakup / computer simulation |
| Paper # | MBE99-95 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 1999/10/27(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Theoretical study on the mechanisms of spontaneous wave breakup of spiral wave in cardiac fibrillation |
| Sub Title (in English) | |
| Keyword(1) | tachyarrhythmia |
| Keyword(2) | spiral wave |
| Keyword(3) | fibrillation |
| Keyword(4) | spontaneous wave breakup |
| Keyword(5) | computer simulation |
| 1st Author's Name | Takashi Ashihara |
| 1st Author's Affiliation | First Department of Internal Medicine, Shiga University of Medical Science,() |
| 2nd Author's Name | Tsunetoyo Namba |
| 2nd Author's Affiliation | Department of Cardiovascular Medicine, Okayama University Medical School, |
| 3rd Author's Name | Tohru Suzuki |
| 3rd Author's Affiliation | National Cardiovascular Center Research Institute, |
| 4th Author's Name | Takanori Ikeda |
| 4th Author's Affiliation | Third Department of Internal Medicine, Toho University School of Medicine, Ohashi Hospital |
| 5th Author's Name | Makoto Ito |
| 5th Author's Affiliation | First Department of Internal Medicine, Shiga University of Medical Science, |
| 6th Author's Name | Masahiko Kinoshita |
| 6th Author's Affiliation | First Department of Internal Medicine, Shiga University of Medical Science, |
| 7th Author's Name | Kazuo Nakazawa |
| 7th Author's Affiliation | National Cardiovascular Center Research Institute, |
| Date | 1999/10/27 |
| Paper # | MBE99-95 |
| Volume (vol) | vol.99 |
| Number (no) | 392 |
| Page | pp.pp.- |
| #Pages | 8 |
| Date of Issue | |