Presentation 2002/3/11
Pairing Frequency Dependence of Spike-timing Dependent Plasticity
Hidetoshi URAKUBO, Masataka WATANABE,
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Abstract(in English) Recent studies gave new insight on synaptic plasticity that the sign and magnitude of plasticity depends critically on the precise timing of pre- and post-synaptic firing, which is termed the spike-timing dependent plasticity (STDP). To examine the generalized behavior of this plasticity, we quantified [Ca2+]in transient in a spine by simulating the pairing experiment of a hippocampal CA1 pyramidal cell. This simulation showed the robustness of timing window at low frequency, and predicts any timing LTP at high frequency.
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Keyword(in English) STDP / Pairing experiment / Ca2+ concentration / Compartment model
Paper # NC2001-162
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Committee NC
Conference Date 2002/3/11(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
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Title (in English) Pairing Frequency Dependence of Spike-timing Dependent Plasticity
Sub Title (in English)
Keyword(1) STDP
Keyword(2) Pairing experiment
Keyword(3) Ca2+ concentration
Keyword(4) Compartment model
1st Author's Name Hidetoshi URAKUBO
1st Author's Affiliation Department of Quantum Engineering and Systems Science, The University of Tokyo()
2nd Author's Name Masataka WATANABE
2nd Author's Affiliation Department of Quantum Engineering and Systems Science, The University of Tokyo
Date 2002/3/11
Paper # NC2001-162
Volume (vol) vol.101
Number (no) 735
Page pp.pp.-
#Pages 7
Date of Issue