Presentation 2002/3/13
Prion protein : Including the interaction between prion protein and reactive oxygen species
Ikuko Ueno,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) Abnormal prion protein, thought to be the causative factor of transmissible spongiform encephalopathy, is derived from the normal cellular prion gene present widely in the brain and other tissues of human and animals. It is believed that the abnormal prion protein, conformationally different from the normal cellular isoform, is generated in the process of the post-translational modification and gets the unusual transmissible and harmful characteristics. For these characteristics of the abnormal prion protein satisfactory explanations have still not given. Interactions between the prion protein and reactive oxygen species have been reported suggesting implication of this interaction in the characteristics of the abnormal prion protein.
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Keyword(in English) prion protein / prion gene / transmissible / spongiform / encephalopathy / reactive oxygen
Paper # SSS2001-37
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Committee SSS
Conference Date 2002/3/13(1days)
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Language JPN
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Title (in English) Prion protein : Including the interaction between prion protein and reactive oxygen species
Sub Title (in English)
Keyword(1) prion protein
Keyword(2) prion gene
Keyword(3) transmissible
Keyword(4) spongiform
Keyword(5) encephalopathy
Keyword(6) reactive oxygen
1st Author's Name Ikuko Ueno
1st Author's Affiliation Yashio Institute of Environmental Sciences()
Date 2002/3/13
Paper # SSS2001-37
Volume (vol) vol.101
Number (no) 739
Page pp.pp.-
#Pages 2
Date of Issue