| Presentation | 2005/3/22 Bridging Cell and Network Dynamics : Virtual Physiological Experiment with NEURON simulator Toru AONISHI, Hiroyoshi MIYAKAWA, Masashi INOUE, Masato OKADA, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We would bridge a gap between cell and network dynamics by collaboration of theorists and physiologists through the commonage of the NEURON simulator. The effect of a dendritic backpropagation on neural interaction has not yet elucidated adequately. A membrane can be modeled by a parallel circuit composed of nonlinear voltage-dependent inward currents and outward currents. In this case, if the inward current and outward current are balanced, the effective membrane impedance diverges to ±∞. This singularity is universal in nerve membranes. By using the NEURON simulator, it was demonstrated that an EPSP collided with a backpropagating action potential was dramatically changed by the regulation of the outward current, reflecting the balancing singularity. Next, we measured phase response curves of a single neuron, and then, we estimated the dynamics of neural networks. It was demonstrated that a network dynamics was dramatically changed by the regulation of the outward current in the mode of the backpropagation generation, reflecting the balancing singularity. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Dendrite / Backpropagating Action Potential / EPSP / A channel / Singular point / NEURON Simulator |
| Paper # | NC2004-177 |
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| Committee | NC |
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| Conference Date | 2005/3/22(1days) |
| Place (in Japanese) | (See Japanese page) |
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| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Bridging Cell and Network Dynamics : Virtual Physiological Experiment with NEURON simulator |
| Sub Title (in English) | |
| Keyword(1) | Dendrite |
| Keyword(2) | Backpropagating Action Potential |
| Keyword(3) | EPSP |
| Keyword(4) | A channel |
| Keyword(5) | Singular point |
| Keyword(6) | NEURON Simulator |
| 1st Author's Name | Toru AONISHI |
| 1st Author's Affiliation | Tokyo Institute of Technology:Brain Science Institute, RIKEN() |
| 2nd Author's Name | Hiroyoshi MIYAKAWA |
| 2nd Author's Affiliation | Tokyo University of Pharmacy and Life Science |
| 3rd Author's Name | Masashi INOUE |
| 3rd Author's Affiliation | Tokyo University of Pharmacy and Life Science |
| 4th Author's Name | Masato OKADA |
| 4th Author's Affiliation | The University of Tokyo:Brain Science Institute, RIKEN:Intelligent Cooperation and Control |
| Date | 2005/3/22 |
| Paper # | NC2004-177 |
| Volume (vol) | vol.104 |
| Number (no) | 759 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |