| Presentation | 2005-03-25 How Multiple Feedback Loops Enhance the Entrainment Ability in Circadian Clock Systems ? : Phase Dynamics in the Interlocked Feedback Model of Drosophila Cirdadian Clock Hisa-Aki TANAKA, Takashi SHIMADA, Tomoki MAEGAWA, Daisuke OHTA, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | In this study, we analyze the following question; How multiple feedback loops enhance the entrainment ability in circadian clock systems ? For this purpose, we focus on the interlocked feedback model of Drosophila circadian clock which is one of the most elaborated models consistently explaining several important aspects known experimentally. For the single-cell entrainment ability in this system subject to weak light inputs, the whole dynamics can be reduced to a simple phase equation governing the system's circadian rhythms. By analyzing such phase equations for the wild-type and various (experimantally known) mutants, we find that the entrainment ability is significantly enhanced in the multiple feedback loops, as opposed to a single feedback loop in the mutant systems. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | circadian clock / multiple feedback loops / entrainment / Drosophila |
| Paper # | NLP2004-117 |
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| Committee | NLP |
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| Conference Date | 2005/3/18(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Nonlinear Problems (NLP) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | How Multiple Feedback Loops Enhance the Entrainment Ability in Circadian Clock Systems ? : Phase Dynamics in the Interlocked Feedback Model of Drosophila Cirdadian Clock |
| Sub Title (in English) | |
| Keyword(1) | circadian clock |
| Keyword(2) | multiple feedback loops |
| Keyword(3) | entrainment |
| Keyword(4) | Drosophila |
| 1st Author's Name | Hisa-Aki TANAKA |
| 1st Author's Affiliation | Department of Electronic Engineering, The University of Electro-Communications (UEC)() |
| 2nd Author's Name | Takashi SHIMADA |
| 2nd Author's Affiliation | Institute of Molecular and Cellular Biosciences, The University of Tokyo |
| 3rd Author's Name | Tomoki MAEGAWA |
| 3rd Author's Affiliation | Department of Electronic Engineering, The University of Electro-Communications (UEC) |
| 4th Author's Name | Daisuke OHTA |
| 4th Author's Affiliation | Department of Electronic Engineering, The University of Electro-Communications (UEC) |
| Date | 2005-03-25 |
| Paper # | NLP2004-117 |
| Volume (vol) | vol.104 |
| Number (no) | 753 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |