Presentation | 2004/11/19 Synaptic Connection Strength Controlled by Complex Activity of the Hippocampal CA3 Through STDP : A Hippocampal Model Daisuke SHIMADA, Hatsuo HAYASHI, Motoharu YOSHIDA, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | It has been found that plastic change in the synaptic weight depends on the spike-timing of pre and postsynaptic neurons. This is called spike-timing-dependent plasticity (STDP). We will show that connection weight of the Schaffer collateral synapses may be controlled at a proper strength and maintained by complex neuronal activity of CA3 using a hippocampal network model. It is also demonstrated that the connection strength of Schaffer collateral synapses recovers to the augmented state even if the synaptic weight is temporarily disturbed by a periodic perforant path signal as a cue for memory recall. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | Hippocampal network model / STDP / Enhancement of Schaffer collateral synapses / Spontaneous activity of CA3 |
Paper # | NLP2004-69,NC2004-85 |
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Committee | NLP |
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Conference Date | 2004/11/19(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Registration To | Nonlinear Problems (NLP) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Synaptic Connection Strength Controlled by Complex Activity of the Hippocampal CA3 Through STDP : A Hippocampal Model |
Sub Title (in English) | |
Keyword(1) | Hippocampal network model |
Keyword(2) | STDP |
Keyword(3) | Enhancement of Schaffer collateral synapses |
Keyword(4) | Spontaneous activity of CA3 |
1st Author's Name | Daisuke SHIMADA |
1st Author's Affiliation | Graduate School of Life Science and System Engineering, Kyushu Institute of Technology() |
2nd Author's Name | Hatsuo HAYASHI |
2nd Author's Affiliation | Graduate School of Life Science and System Engineering, Kyushu Institute of Technology |
3rd Author's Name | Motoharu YOSHIDA |
3rd Author's Affiliation | Department of Neurology and Neurosurgery, McGill University |
Date | 2004/11/19 |
Paper # | NLP2004-69,NC2004-85 |
Volume (vol) | vol.104 |
Number (no) | 471 |
Page | pp.pp.- |
#Pages | 6 |
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