| Presentation | 2005-05-13 Orexin effects on hypothalamic medial preoptic neurons in rats examined by cytosolic Ca^<2+> imaging Masafumi TAKATSUNA, Kohjiro WATANABE, Kazuki NAKAJIMA, Kazuo SASAKI, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Effects of orexin-A (ORX-A) and orexin-B (ORX-B) on medial preoptic area (MPOA) neurons were examined in rat brain slice preparations by means of a cytosolic Ca^<2+> concentration ([Ca^<2+>]i) imaging. ORXs increased [Ca^<2+>]i in MPOA neurons mainly through the direct effect to OX_2 receptors. The increase of [Ca^<2+>]i was mediated via the opening of Ni^<2+>-sensitive voltage-dependent Ca^<2+> channels. Results suggest that orexin-activated MPOA neurons play a role in the regulation of sexual arousal as well as sleep-wakefulness. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Medial preoptic area / MPOA / Orexin / [Ca^<2+>]i imaging |
| Paper # | MBE2005-10 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2005/5/6(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Orexin effects on hypothalamic medial preoptic neurons in rats examined by cytosolic Ca^<2+> imaging |
| Sub Title (in English) | |
| Keyword(1) | Medial preoptic area |
| Keyword(2) | MPOA |
| Keyword(3) | Orexin |
| Keyword(4) | [Ca^<2+>]i imaging |
| 1st Author's Name | Masafumi TAKATSUNA |
| 1st Author's Affiliation | Faculty of Engineering, Toyama University() |
| 2nd Author's Name | Kohjiro WATANABE |
| 2nd Author's Affiliation | Faculty of Engineering, Toyama University |
| 3rd Author's Name | Kazuki NAKAJIMA |
| 3rd Author's Affiliation | Faculty of Engineering, Toyama University |
| 4th Author's Name | Kazuo SASAKI |
| 4th Author's Affiliation | Faculty of Engineering, Toyama University |
| Date | 2005-05-13 |
| Paper # | MBE2005-10 |
| Volume (vol) | vol.105 |
| Number (no) | 46 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |