Presentation 2004/5/21
Brain Activity of Anesthetized Guinea Pig Evoked by Auditory Oddball Sequence
Shuntaro OKAZAKI, Shin'ichiro KANOH, Kazum SHIBUYA, Kana TAKAURA, Kotaro TAKEDA, Minoru TSUKADA, Kotaro OKA,
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Abstract(in English) Many studies of mismatch negativity (MMN) have been performed to investigate functional discrimination of sound in the brain. MMN is induced oddball sequence consisting of infrequent (deviant) sound stimuli and frequent (standard) sound stimuli. The MMN is considered to reflect sensory memory to standard stimuli and pre-attentive comparison between standard and deviant stimuli. It occurs, whereby, in the absence of attention and even under anesthesia. However, the neural mechanisms of the MMN are remained unclear. In this study, we measured temporal electroencephalogram (EEG) and hippocampal local field potential (LFP) simultaneously in anesthetized guinea pigs to the oddball sequence of sound duration. Consequently, MMN was not appeared in temporal EEG but hippocampal LFP exhibited MMN-like negative potential.
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Keyword(in English) Auditory cortex / Hippocampus / Mismatch negativity / Field potential / Electroencephalogram
Paper # NC2004-5
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Committee NC
Conference Date 2004/5/21(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Brain Activity of Anesthetized Guinea Pig Evoked by Auditory Oddball Sequence
Sub Title (in English)
Keyword(1) Auditory cortex
Keyword(2) Hippocampus
Keyword(3) Mismatch negativity
Keyword(4) Field potential
Keyword(5) Electroencephalogram
1st Author's Name Shuntaro OKAZAKI
1st Author's Affiliation School of Fundamental Science and Technology, Graduate School of Keio University()
2nd Author's Name Shin'ichiro KANOH
2nd Author's Affiliation Department of Electronic Engineering, Graduate School of Engineering, Tohoku University
3rd Author's Name Kazum SHIBUYA
3rd Author's Affiliation Faculty of Engineering, Tamagawa University
4th Author's Name Kana TAKAURA
4th Author's Affiliation School of Fundamental Science and Technology, Graduate School of Keio University
5th Author's Name Kotaro TAKEDA
5th Author's Affiliation School of Fundamental Science and Technology, Graduate School of Keio University
6th Author's Name Minoru TSUKADA
6th Author's Affiliation Faculty of Engineering, Tamagawa University
7th Author's Name Kotaro OKA
7th Author's Affiliation School of Fundamental Science and Technology, Graduate School of Keio University
Date 2004/5/21
Paper # NC2004-5
Volume (vol) vol.104
Number (no) 99
Page pp.pp.-
#Pages 4
Date of Issue