| Presentation | 2002/3/11 A quantitative evaluation of the influence of neuron shape changes on the firing characteristics Seiichi SAKATANI, Akira HIROSE, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | The neuron is highly full of variety in its shape and size. Each neuron changes the shape to adapt to the region and function in the nervous system. The influence of neuron shape on the firing characteristics, however, has still been unclear. In this paper, we evaluate numerically the influence of the changes of the neuron shape on the firing characteristics. We construct a new neuronal model of the pyramidal cell at the CA3 hippocampus based on the compartmental model to analyze quantitatively the firing characteristics. We find the following facts. First, the firing frequency is higher if the shape of the apical-dendrite hillock is sharper. Secondly, the firing latency is shorter for the apical-dendrite synaptic stimulus if the shape of the apical-dendrite hillock is sharper. These facts lead to a hypothesis that the shape has changed to response more sensitively to the stimulus at the apical dendrite. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | neuron shape / pyramidal cell / hippocampus / CA3 / firing rate / firing latency |
| Paper # | MBE2001-168 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2002/3/11(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | A quantitative evaluation of the influence of neuron shape changes on the firing characteristics |
| Sub Title (in English) | |
| Keyword(1) | neuron shape |
| Keyword(2) | pyramidal cell |
| Keyword(3) | hippocampus |
| Keyword(4) | CA3 |
| Keyword(5) | firing rate |
| Keyword(6) | firing latency |
| 1st Author's Name | Seiichi SAKATANI |
| 1st Author's Affiliation | Department of Frontier Informatics, Graduate School of Frontier Sciences, The University of Tokyo() |
| 2nd Author's Name | Akira HIROSE |
| 2nd Author's Affiliation | Department of Frontier Informatics, Graduate School of Frontier Sciences, The University of Tokyo |
| Date | 2002/3/11 |
| Paper # | MBE2001-168 |
| Volume (vol) | vol.101 |
| Number (no) | 733 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |