Presentation 2002/9/13
Method for Calculating the Interaction (Van der Waals ) Potential among the Cylindrical Polypeptides that Carry Helically Arranged Point Charges on Their Surfaces.
H Hirayama,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) We proposed a geometrical method to calculate the interaction potential among the cylindrical circular polypeptides that constitute the ion selective channel pore on the excitable biological membrane. An ion channel pore is composed of 5 to 6 subunits each of which is further constituted from 6 polypeptides. They carry negative electrical potentials on their surfaces with helical arrangement. When the channel transits between open and closed formation,the polypeptide deforms so as to minimize the potential field of an entire molecule of the channel. The present paper introduced a geometric method to characterize interaction among the helically distributed point charges on the polypeptides. We introduced the Van der Waals potential for characterizing the interaction among the channel composer cylindrical polypeptides.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Ion selective channel / Cylindrical circular polypeptides / interaction potential / Van der Waals force.
Paper # OME2002-59
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Committee OME
Conference Date 2002/9/13(1days)
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Registration To Organic Material Electronics (OME)
Language ENG
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Method for Calculating the Interaction (Van der Waals ) Potential among the Cylindrical Polypeptides that Carry Helically Arranged Point Charges on Their Surfaces.
Sub Title (in English)
Keyword(1) Ion selective channel
Keyword(2) Cylindrical circular polypeptides
Keyword(3) interaction potential
Keyword(4) Van der Waals force.
1st Author's Name H Hirayama
1st Author's Affiliation Department of Public Health Asahikawa medical college.()
Date 2002/9/13
Paper # OME2002-59
Volume (vol) vol.102
Number (no) 327
Page pp.pp.-
#Pages 7
Date of Issue