Presentation | 2001/11/22 Modeling Circadian System with Feedback Mechanisms Keisuke YAMAMOTO, Mitsuyuki NAKAO, Norihiko KATAYAMA, Mitsuaki YAMAMOTO, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | On the human circadian system, there exist the reports that non-photic time-cues work on the sleep-wake rhythm as well as the circadian pacemaker. Since sleep-wake pattern is under control of circadian pacemaker while non-photic time-cues affect circadian pacemaker through sleep-wake schedule, there exist feedback mechanisms in the circadian system. In this study, the phase dynamic model with feedback mechanisms was constructed. On the base of two oscillator model, Osc I and Osc II drives melatonin rhythm and sleep-wake rhythm, respectively. In addition, the overt sleep-wake rhythm is introduced, which behaves like an oscillator. Three oscillators are mutually coupled, where the cumulative feedback mechanisms are implemented by modulating the coupling strength. The model constructed here gave us the behavior and the interpretation of circadian system. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | sleep-wake rhythm / feedback mechanism / two oscillator model / non-photic time-cue / re-entrainment |
Paper # | MBE2001-106 |
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Conference Information | |
Committee | MBE |
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Conference Date | 2001/11/22(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | ME and Bio Cybernetics (MBE) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Modeling Circadian System with Feedback Mechanisms |
Sub Title (in English) | |
Keyword(1) | sleep-wake rhythm |
Keyword(2) | feedback mechanism |
Keyword(3) | two oscillator model |
Keyword(4) | non-photic time-cue |
Keyword(5) | re-entrainment |
1st Author's Name | Keisuke YAMAMOTO |
1st Author's Affiliation | Graduate School of Information Sciences, Tohoku University() |
2nd Author's Name | Mitsuyuki NAKAO |
2nd Author's Affiliation | Graduate School of Information Sciences, Tohoku University |
3rd Author's Name | Norihiko KATAYAMA |
3rd Author's Affiliation | Graduate School of Information Sciences, Tohoku University |
4th Author's Name | Mitsuaki YAMAMOTO |
4th Author's Affiliation | Graduate School of Information Sciences, Tohoku University |
Date | 2001/11/22 |
Paper # | MBE2001-106 |
Volume (vol) | vol.101 |
Number (no) | 478 |
Page | pp.pp.- |
#Pages | 8 |
Date of Issue |