| Presentation | 2000/11/23 Evaluation of the critical mass hypothesis of the ventricular fibrillation with a mathematical model. : -Simulation study- Sunao TODA, Takashi ASHIHARA, Toru SUZUKI, Tsunetoyo NAMBA, Ayaka KAWASE, Takanori IKEDA, Masashi INAGAKI, Jun WATANABE, Kunio SHIRATO, Kazuo NAKAZAWA, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | The critical mass hypothesis says critical amount of myocardium is needed to maintain the ventricular fibrillation. We evaluated this hypothesis by using 3-D tissue models with the Luo-Rudy model. We constructed a parallelepipedal slab and a human ventricular shaped model. The critical mass in each model was 480, 000 units and 420, 000-550, 000 units, respectively, which corresponded to 7.2-9.4cm^3 of the myocardium. When the tissue volume was the same, the fibrillation became difficult to maintain as the surface area of the tissue widened. The fibrillation terminated when the surface to volume ratio (S/V) was over 3.5. We concluded that the maintenance of the fibrillation is determined by the S/V of the tissue rather than only the critical mass. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | ventricular fibrillation / critical mass hypothesis / spiral wave / Luo-Rudy model |
| Paper # | MBE2000-96 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2000/11/23(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Evaluation of the critical mass hypothesis of the ventricular fibrillation with a mathematical model. : -Simulation study- |
| Sub Title (in English) | |
| Keyword(1) | ventricular fibrillation |
| Keyword(2) | critical mass hypothesis |
| Keyword(3) | spiral wave |
| Keyword(4) | Luo-Rudy model |
| 1st Author's Name | Sunao TODA |
| 1st Author's Affiliation | National Cardiovascular Center Research Institute : Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine() |
| 2nd Author's Name | Takashi ASHIHARA |
| 2nd Author's Affiliation | National Cardiovascular Center Research Institute : First Department of Internal Medicine, Shiga University of Medical Science |
| 3rd Author's Name | Toru SUZUKI |
| 3rd Author's Affiliation | National Cardiovascular Center Research Institute |
| 4th Author's Name | Tsunetoyo NAMBA |
| 4th Author's Affiliation | Department of Medical Technology, Kagawa Prefectural College of Health Science |
| 5th Author's Name | Ayaka KAWASE |
| 5th Author's Affiliation | Third Department of Internal Medicine, Ohashi Hospital, Toho University |
| 6th Author's Name | Takanori IKEDA |
| 6th Author's Affiliation | Third Department of Internal Medicine, Ohashi Hospital, Toho University |
| 7th Author's Name | Masashi INAGAKI |
| 7th Author's Affiliation | National Cardiovascular Center Research Institute |
| 8th Author's Name | Jun WATANABE |
| 8th Author's Affiliation | Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine |
| 9th Author's Name | Kunio SHIRATO |
| 9th Author's Affiliation | Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine |
| 10th Author's Name | Kazuo NAKAZAWA |
| 10th Author's Affiliation | National Cardiovascular Center Research Institute |
| Date | 2000/11/23 |
| Paper # | MBE2000-96 |
| Volume (vol) | vol.100 |
| Number (no) | 478 |
| Page | pp.pp.- |
| #Pages | 8 |
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