Presentation | 2000/11/23 Long-term potentiation of synaptically activated increases in calcium concentration in hippocampal dentate dyrus cells Masato OZAWA, Norihiro KATAYAMA, Mitsuyuki NAKAO, Mitsuaki YAMAMOTO, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | Intracellular Ca^2+ is known to play important role for regulation and control of many cellular chemical processes. In this study, increase in intracellular Ca^2+ concentration(△[Ca^2+])evoked by a burst stimulation (20Hz, 5pulses)to perforant path(PP)synapses were measured in dentate granule cells of rat hippocampal slices by means of laser scanning microscope. After a tetanic stimulation(100Hz, 100pulses)to the PP-synapses, some cells showed increase in △[Ca^2+]evoked by PP-synaptic inputs for 1 hour. Since the △[Ca^2+]is known to associated with the firing of granule cells, the result is expected to reflect the increase of firing probabirily of the cells in response to the synaptic inputs caused by the long-term potentiation at the synapses. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | neuron / hippocampus / Long-term potentiation / calcium imaging / laser scanning microscope |
Paper # | MBE2000-94 |
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Conference Information | |
Committee | MBE |
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Conference Date | 2000/11/23(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | ME and Bio Cybernetics (MBE) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Long-term potentiation of synaptically activated increases in calcium concentration in hippocampal dentate dyrus cells |
Sub Title (in English) | |
Keyword(1) | neuron |
Keyword(2) | hippocampus |
Keyword(3) | Long-term potentiation |
Keyword(4) | calcium imaging |
Keyword(5) | laser scanning microscope |
1st Author's Name | Masato OZAWA |
1st Author's Affiliation | Graduate School of Information Sciences, Tohoku University() |
2nd Author's Name | Norihiro KATAYAMA |
2nd Author's Affiliation | Graduate School of Information Sciences, Tohoku University |
3rd Author's Name | Mitsuyuki NAKAO |
3rd Author's Affiliation | Graduate School of Information Sciences, Tohoku University |
4th Author's Name | Mitsuaki YAMAMOTO |
4th Author's Affiliation | Graduate School of Information Sciences, Tohoku University |
Date | 2000/11/23 |
Paper # | MBE2000-94 |
Volume (vol) | vol.100 |
Number (no) | 478 |
Page | pp.pp.- |
#Pages | 7 |
Date of Issue |