| Presentation | 2000/3/15 Mechanism of apoptosis-like cell death and the changes of contraction rhythm in cultured cardiac myocytes Tadashi Saitoh, Masaki Kakutani, Hideomi Satoh, Yoshiko Yamauchi, Koichi Kawahara, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | In this study, we investigated the mechanism of CHX-induced cardiomyocyte-specific apoptosis-like cell death in cardiac myocyte-fibroblast co-cultures from neonatal rats, and analyzed the changes of contraction rhythm associated with the cell death. Treatment of the culture with CHX resulted in the increase of contraction intervals and fluctuations in the contraction rhythm. The CHX-induced apoptosis-like cardiac myocyte death was suppressed or delayed by the cell-permeable reactive oxygen species (ROS) scavenger, MnTBAP. This result suggests a possible involvement of ROS in such CHX-induced myocyte death. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | cardiac myocyte / apoptosis / MnTBAP / conraction rhythm |
| Paper # | MBE99-164 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2000/3/15(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Mechanism of apoptosis-like cell death and the changes of contraction rhythm in cultured cardiac myocytes |
| Sub Title (in English) | |
| Keyword(1) | cardiac myocyte |
| Keyword(2) | apoptosis |
| Keyword(3) | MnTBAP |
| Keyword(4) | conraction rhythm |
| 1st Author's Name | Tadashi Saitoh |
| 1st Author's Affiliation | Research Institute for Electronic Science, Hokkaido University() |
| 2nd Author's Name | Masaki Kakutani |
| 2nd Author's Affiliation | Research Institute for Electronic Science, Hokkaido University |
| 3rd Author's Name | Hideomi Satoh |
| 3rd Author's Affiliation | Research Institute for Electronic Science, Hokkaido University |
| 4th Author's Name | Yoshiko Yamauchi |
| 4th Author's Affiliation | Research Institute for Electronic Science, Hokkaido University |
| 5th Author's Name | Koichi Kawahara |
| 5th Author's Affiliation | Research Institute for Electronic Science, Hokkaido University |
| Date | 2000/3/15 |
| Paper # | MBE99-164 |
| Volume (vol) | vol.99 |
| Number (no) | 688 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |