| Presentation | 2000/3/14 Immunosuppression by Photodynamic Therapy, as determined by the survival of mouse skin allografts Y. Kitamura, S. Jyoudai, Y. Umebayashi, Y. Miyamoto, T. Nisisaka, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | [Introduction]Photodynamic Therapy (PDT) is a treatment of malignant tumors employing the interaction of photosensitizer with laser light in the presence of molecular oxygen. Recently, some investigations have demonstrated that the PDT possesses immunosupprssion effect. In this study, we estimated the effect of PDT on immunosuppression, as determined by survival of skin allografts, and examined its mechanism from view points of immune cells. [Materials and Methods]Allogeneic skin from BALB/cAN donor mice was transplanted onto the PDT treated recipient C3H/HeN mice. In addition, activated immune cell including activated helper T cell and cytotoxic T cell were detected by flow cytometer. [Results and Discussion]The survival period of skin allografts was prolonged by PDT treatment. This prolongation of allografts survival would be ascribed to the depletion of activated immune cells such as helper T cells or cytotoxic T cells. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Photodynamic Therapy / Skin grafting / Graft rejection / Flow Cytometer |
| Paper # | MBE99-150 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 2000/3/14(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Immunosuppression by Photodynamic Therapy, as determined by the survival of mouse skin allografts |
| Sub Title (in English) | |
| Keyword(1) | Photodynamic Therapy |
| Keyword(2) | Skin grafting |
| Keyword(3) | Graft rejection |
| Keyword(4) | Flow Cytometer |
| 1st Author's Name | Y. Kitamura |
| 1st Author's Affiliation | Graduate School of Material Science, Japan Advanced Institute of Science and Technology() |
| 2nd Author's Name | S. Jyoudai |
| 2nd Author's Affiliation | Graduate School of Material Science, Japan Advanced Institute of Science and Technology |
| 3rd Author's Name | Y. Umebayashi |
| 3rd Author's Affiliation | Graduate School of Material Science, Japan Advanced Institute of Science and Technology |
| 4th Author's Name | Y. Miyamoto |
| 4th Author's Affiliation | Graduate School of Material Science, Japan Advanced Institute of Science and Technology |
| 5th Author's Name | T. Nisisaka |
| 5th Author's Affiliation | Graduate School of Material Science, Japan Advanced Institute of Science and Technology |
| Date | 2000/3/14 |
| Paper # | MBE99-150 |
| Volume (vol) | vol.99 |
| Number (no) | 687 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |