Presentation 1998/10/13
Systematic analysis of heat production mechanisms in thermoregulation of homeotherms.
Takayoshi HOSONO, Kazuyuki KANOSUE, Kenzo AKAZAWA,
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Abstract(in English) To analyze heat production systems of homeothermal animals, we investigated shivering and non-shivering thermogenesis of rats and composed its mathematical model based on our findings.Heat-producing signals in shivering and non-shivering thermogenesis were tonically generated by posterior hypothalamus and ventromedial nucleus, respectively.These signals were suppressed by signals in the preoptic area.When the temperature in preoptic area increased, both heat productions were inhibited.Both their neuronal circuits seemed independent each other.Step response of the model developed by these physiological facts simulated well actual thermoregulatory physiological responses against a cold load.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) thermoregulation / heat production / Shivering / non-shivering thermogenesis / model / simulation
Paper # MBE98-80
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Committee MBE
Conference Date 1998/10/13(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Systematic analysis of heat production mechanisms in thermoregulation of homeotherms.
Sub Title (in English)
Keyword(1) thermoregulation
Keyword(2) heat production
Keyword(3) Shivering
Keyword(4) non-shivering thermogenesis
Keyword(5) model
Keyword(6) simulation
1st Author's Name Takayoshi HOSONO
1st Author's Affiliation Department of Physiology, School of Allied Health Sciences, Osaka University Faculty of Medicine()
2nd Author's Name Kazuyuki KANOSUE
2nd Author's Affiliation Department of Physiology, School of Allied Health Sciences, Osaka University Faculty of Medicine
3rd Author's Name Kenzo AKAZAWA
3rd Author's Affiliation Department of Computer and Systems Engineering, Faculty of Engineering, Kobe University
Date 1998/10/13
Paper # MBE98-80
Volume (vol) vol.98
Number (no) 314
Page pp.pp.-
#Pages 8
Date of Issue