| Presentation | 1998/5/29 Approach Using Computer Simulation to Dynamic Process of "Guardian of the Genome" p53 Tohru Noda, Toyomasa Hatakeyama, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | p53 has been named "guardian of the genome" by many researchers. Dynamic process of p53 in rat liver cells excised has been reported, because this protein suppresses abnormal cell proliferation such as cancer cells and controls apoptosis. We propose a mathematical model of this dynamic process and practice computer simulation. In the case, unknown parameters is detected by means of the optimum parameter method. Performance of the simulation led to some interesting opinions. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | p53 / DNA / mRNA / dynamic process / simulation |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 1998/5/29(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Approach Using Computer Simulation to Dynamic Process of "Guardian of the Genome" p53 |
| Sub Title (in English) | |
| Keyword(1) | p53 |
| Keyword(2) | DNA |
| Keyword(3) | mRNA |
| Keyword(4) | dynamic process |
| Keyword(5) | simulation |
| 1st Author's Name | Tohru Noda |
| 1st Author's Affiliation | Faculty of Engineering, Toyama University() |
| 2nd Author's Name | Toyomasa Hatakeyama |
| 2nd Author's Affiliation | Faculty of Engineering, Toyama University |
| Date | 1998/5/29 |
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| Volume (vol) | vol.98 |
| Number (no) | 94 |
| Page | pp.pp.- |
| #Pages | 6 |
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