Presentation | 1994/12/16 APPLICATION OF OPTIMAL CONTROL THEORY FOR ANALYSIS OF MECHANISM OF cAMP PRODUCTION DURING INTRA CELLULAR SIGNAL TRANSMISSION : INTER CONVERSION MECHANISM AMONG RECEPTOR, ATP AND HORMONE. Hirofumi Hirayama, Takashi Gotou, Masahito Nishimura, Yuzo Fukuyama, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | To know the mechanism of production of cAMP in response to Hormone,we have proposed an optimal control mechanism for the inter converting system among receptor,ATP and hormone complexes. The instantaneous equilifbrium state was expressed by linear differential equations assuming that the ATP and Hormone were supplied sufficiently.The performance function minimized included the rate of changes in these complexes and the control input to drive the production of each complexes.The optimal trajectories of concentrations of these complexes and the optimal control inputs were seriously influenced by hormone but little by ATP.The time courses of the optimal inputs were reverted by increase in hormone. Present analysis is available for evaluation of the control mechanism of receptor,ATP and hormone interactions. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | cAMP / Hormone / Receptor / Optimal control / Agonistic reaction |
Paper # | MBE94-101 |
Date of Issue |
Conference Information | |
Committee | MBE |
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Conference Date | 1994/12/16(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | ME and Bio Cybernetics (MBE) |
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Language | ENG |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | APPLICATION OF OPTIMAL CONTROL THEORY FOR ANALYSIS OF MECHANISM OF cAMP PRODUCTION DURING INTRA CELLULAR SIGNAL TRANSMISSION : INTER CONVERSION MECHANISM AMONG RECEPTOR, ATP AND HORMONE. |
Sub Title (in English) | |
Keyword(1) | cAMP |
Keyword(2) | Hormone |
Keyword(3) | Receptor |
Keyword(4) | Optimal control |
Keyword(5) | Agonistic reaction |
1st Author's Name | Hirofumi Hirayama |
1st Author's Affiliation | The department of Public Health,Asahikawa medical college() |
2nd Author's Name | Takashi Gotou |
2nd Author's Affiliation | The department of Public Health,Asahikawa medical college |
3rd Author's Name | Masahito Nishimura |
3rd Author's Affiliation | The department of Public Health,Asahikawa medical college |
4th Author's Name | Yuzo Fukuyama |
4th Author's Affiliation | The department of Public Health,Asahikawa medical college |
Date | 1994/12/16 |
Paper # | MBE94-101 |
Volume (vol) | vol.94 |
Number (no) | 416 |
Page | pp.pp.- |
#Pages | 8 |
Date of Issue |