Presentation 1993/5/28
Models for Spontaneous Neuronal Activity : From BVP Model to mRIC Model
Taishin Nomura, Shunsuke Sato, Shinji Doi, Jose P. Segundo, Michael D. Stiber,
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Abstract(in English) The response characteristics of the stable limit cycle oscillators which have the slow, fast dynamics to periodic pulsatile stimulation are investigated.Repetitive firing phenomenon with "spikting" dynamics as in the living pacemaker neu rons are modeled by the two oscillators with different complerities.Model′s global bifurcation diagrams are analyzed by u sing one dimensional map(PTC).In these oscillators,compaxing with non-spiking oscillators,the periodic points of small period of the PTC are stabilized against the variation of the period and intensity of stimulation,while chaotic regions in the parameter space are spread.Bistabilities are shown to be observable in the wide range of parameters.These facts are discussed qualitatively with the the dynamics of the membrane potential such as threshold, action potential and the sub-threshold voltage region activity of the neurons.
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Keyword(in English) pacemaker neuron / isochron / phase transition curve / chaos
Paper # MBE93-25
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Committee MBE
Conference Date 1993/5/28(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Models for Spontaneous Neuronal Activity : From BVP Model to mRIC Model
Sub Title (in English)
Keyword(1) pacemaker neuron
Keyword(2) isochron
Keyword(3) phase transition curve
Keyword(4) chaos
1st Author's Name Taishin Nomura
1st Author's Affiliation Department of Biophysical Engineering,Faculty of Engineering Science,Osaka University()
2nd Author's Name Shunsuke Sato
2nd Author's Affiliation Department of Biophysical Engineering,Faculty of Engineering Science,Osaka University
3rd Author's Name Shinji Doi
3rd Author's Affiliation Department of Biophysical Engineering,Faculty of Engineering Science,Osaka University
4th Author's Name Jose P. Segundo
4th Author's Affiliation Department of Anatomy and Cell Biology,Brain Research Institute, University of California Los Angeles
5th Author's Name Michael D. Stiber
5th Author's Affiliation Computer Science Department,The Hong Kong University of Science and Technology
Date 1993/5/28
Paper # MBE93-25
Volume (vol) vol.93
Number (no) 84
Page pp.pp.-
#Pages 8
Date of Issue