Presentation 1996/6/20
Neural control of glucose uptake in peripheral muscle during contraction
Ichiro MINEJIMA, Takao NAKAMURA, Masataka KUSUNOKI, Tsutomu HARA, Koichi KAWAHARA,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) To know the neural control mechanism of blood glucose (BG) uptake in contracting peripheral muscle, we electrically stimulated the sciatic nerve of rats to induce contraction of hindlimb muscles, and measured BG and plasma insulin (PI) levels. The BG level temporarily decreased immediately after starting the stimulation, while the PI level did not change. The results suggested that the BG uptake in the contracting hindlimb muscles are regulated by the nervous system. Then, we evaluated influences of hindlimb denervation and effects of pharmacological neuromuscular block. The BG level did not decrease in the both cases, suggesting that a feedback control system including the central nervous system, and afferent signals caused by the muscle contraction are necessary in the control.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) glucose uptake / neural control / denervation / neuromuscular block / rat
Paper # MBE96-31
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Conference Information
Committee MBE
Conference Date 1996/6/20(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Neural control of glucose uptake in peripheral muscle during contraction
Sub Title (in English)
Keyword(1) glucose uptake
Keyword(2) neural control
Keyword(3) denervation
Keyword(4) neuromuscular block
Keyword(5) rat
1st Author's Name Ichiro MINEJIMA
1st Author's Affiliation Research Institute for Electronic Science, Hokkaido University()
2nd Author's Name Takao NAKAMURA
2nd Author's Affiliation Research Institute for Electronic Science, Hokkaido University
3rd Author's Name Masataka KUSUNOKI
3rd Author's Affiliation Internal Medicine, Aichi Medical University
4th Author's Name Tsutomu HARA
4th Author's Affiliation Internal Medicine, Aichi Medical University
5th Author's Name Koichi KAWAHARA
5th Author's Affiliation Research Institute for Electronic Science, Hokkaido University
Date 1996/6/20
Paper # MBE96-31
Volume (vol) vol.96
Number (no) 113
Page pp.pp.-
#Pages 5
Date of Issue