Presentation 1998/3/19
Effect of Alternating Current Stimulation on Function os Immunocyte
Koichi USHIDA, Toshiyuki SHIMOOKA, Koichi SHIMIZU,
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Abstract(in English) The effect of ELF electric current stimulation on the phagocytosis of a macrophages which is one of the immunocytes was investigated. The parameters such as the duration of stimulation, the current density and the frequency of the current were varisd, and the effect on the phagocytosis was evaluated. The fluorescent latex beads with 0.75μm diameter were fed to macrophages, and the degree of phagocytosis was deternined in fluorescent microscopy. As a result, the phagocytosis was suppressend by the electric current stimulation. The difference from the sham exposure case was statistically significant. The change in phagocytosis due to the variation of the above parameters was not statistically significant. The suppression of phagocytosis by electric current stimulation seems to be new findings. It may enable us to control the functions of macrophages.
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Keyword(in English) ELF current / macrophage / phagocytosis
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Committee MBE
Conference Date 1998/3/19(1days)
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Registration To ME and Bio Cybernetics (MBE)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Effect of Alternating Current Stimulation on Function os Immunocyte
Sub Title (in English)
Keyword(1) ELF current
Keyword(2) macrophage
Keyword(3) phagocytosis
1st Author's Name Koichi USHIDA
1st Author's Affiliation Laboratory of Biomedical Systems Enginering, Graduate School of Engineering Hokkaido University()
2nd Author's Name Toshiyuki SHIMOOKA
2nd Author's Affiliation Laboratory of Biomedical Systems Enginering, Graduate School of Engineering Hokkaido University
3rd Author's Name Koichi SHIMIZU
3rd Author's Affiliation Laboratory of Biomedical Systems Enginering, Graduate School of Engineering Hokkaido University
Date 1998/3/19
Paper #
Volume (vol) vol.97
Number (no) 621
Page pp.pp.-
#Pages 6
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