| Presentation | 1997/9/27 On Subjective Effect of Addictive Drug and Temporal Differentiation of Response in Striatum Yasuhiro SAGAWA, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | The relationship between subjective effect (euphoria) of cocaine and dopamine transporter (DAT) occupancy in striatum of basal ganglia has been reported. In this research, it is indicated that the subjective effect are thought to correspond to positive temporal differentiation of an amount of dopmaine (DA) (or of neuronal responses) in striatum. And, by assuming that subjective dysphoria corresponds to negative temporal differentiation of the amount of DA (or of neuronal responses) in striatum, an interesting hypothesis concerning a relationship between euphoria and dysphoria is lead theoretically. Furthermore, relationships among subjective feelings (euphoria and dysphoria), DA in striatum, neuronal responses in striatum, neuronal responses in substantia nigra pars compacta (SNc) and ventral tegmental area (VTA), and reinforcement in learning and action selection are discussed. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | addictive drug / subjective effect / striatum / dopamine / temporal differentiation / reinforcement |
| Paper # | MBE97-80 |
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| Conference Information | |
| Committee | MBE |
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| Conference Date | 1997/9/27(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | ME and Bio Cybernetics (MBE) |
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| Language | ENG |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | On Subjective Effect of Addictive Drug and Temporal Differentiation of Response in Striatum |
| Sub Title (in English) | |
| Keyword(1) | addictive drug |
| Keyword(2) | subjective effect |
| Keyword(3) | striatum |
| Keyword(4) | dopamine |
| Keyword(5) | temporal differentiation |
| Keyword(6) | reinforcement |
| 1st Author's Name | Yasuhiro SAGAWA |
| 1st Author's Affiliation | Department of Biophysical Engineering, Faculty of Engineering Science, Osaka University() |
| Date | 1997/9/27 |
| Paper # | MBE97-80 |
| Volume (vol) | vol.97 |
| Number (no) | 292 |
| Page | pp.pp.- |
| #Pages | 7 |
| Date of Issue | |