Presentation 1996/12/14
Spatio-Temporal Mechanisms of the Calcium System in the Retinal Photoreceptor
Toshihiko OGURA, Yoshimi KAMIYAMA, Shiro USUI,
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Abstract(in English) The retinal photoreceptor is a primary neuron in the visual system, which converts light signal into electrical signal. The intracellular calciurn system in the photoreceptor plays an important role to modulate the phototransduction mechanism and/or ionic current characteristics. In order to clarify the calcium mechanisms, we analyzed the spatio-temporal properties of the intracellular calcium in the photoreceptor by using a calcium imaging system. The results suggest that 1) at the resting state the outer segment of intracellular free Ca^<2+> level was higher than inner segmnet, which is resulted in cGMP activated channels of outer segment, 2) depo-larization of photoreceptor by high K^+ solution increased Ca^<2+> concentration of inner segment, which is generated by voltage activated Ca^<2+> channel.
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Keyword(in English) photoreceptor / intracellular Ca^<2+> concentration, cGMP activated channel / diffusion
Paper # NC96-74
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Committee NC
Conference Date 1996/12/14(1days)
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Registration To Neurocomputing (NC)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Spatio-Temporal Mechanisms of the Calcium System in the Retinal Photoreceptor
Sub Title (in English)
Keyword(1) photoreceptor
Keyword(2) intracellular Ca^<2+> concentration, cGMP activated channel
Keyword(3) diffusion
1st Author's Name Toshihiko OGURA
1st Author's Affiliation Department of Information and Computer Sciences,Toyohashi University of Technology()
2nd Author's Name Yoshimi KAMIYAMA
2nd Author's Affiliation Computer Center,Toyohashi University of Technology
3rd Author's Name Shiro USUI
3rd Author's Affiliation Department of Information and Computer Sciences,Toyohashi University of Technology
Date 1996/12/14
Paper # NC96-74
Volume (vol) vol.96
Number (no) 430
Page pp.pp.-
#Pages 8
Date of Issue