Presentation | 2000/5/4 Analysis of DNA Microarray Images Naoya Ohta, Youhei Hachisu, Tatsuya Akutsu, Asao Fujiyama, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | DNA micorarray is known as a method to obtain information of many different genes by one experiment. In order to effectively use this method, however. we need to automate the image processing part of the method. We describe an image processing algorithm for this purpose. A DNA micorarray image consists of a lot of spots regularly placed in a grid shape. The intensity of each spot corresponds to activeness of a specific gene. Therefore, the function of the image processing algorithm is to identify each spot and to measure its intensity. The algorithm first detects candidates of the spots and determines the angle and position of the grid formed by the spots. Then, it selects correct spots from the candidates using the information of the grid position. Next, the algorithm estimates the background levels of the image by intensity histograms and measure the intensity of each spot. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | DNA microarray / gene network / spot detection / line detection / background level estimation |
Paper # | PRMU2000-9, MI2000-9 |
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Committee | MI |
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Conference Date | 2000/5/4(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Registration To | Medical Imaging (MI) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Analysis of DNA Microarray Images |
Sub Title (in English) | |
Keyword(1) | DNA microarray |
Keyword(2) | gene network |
Keyword(3) | spot detection |
Keyword(4) | line detection |
Keyword(5) | background level estimation |
1st Author's Name | Naoya Ohta |
1st Author's Affiliation | Gunma University() |
2nd Author's Name | Youhei Hachisu |
2nd Author's Affiliation | Gunma University |
3rd Author's Name | Tatsuya Akutsu |
3rd Author's Affiliation | University of Tokyo |
4th Author's Name | Asao Fujiyama |
4th Author's Affiliation | National Institute of Genetics |
Date | 2000/5/4 |
Paper # | PRMU2000-9, MI2000-9 |
Volume (vol) | vol.100 |
Number (no) | 45 |
Page | pp.pp.- |
#Pages | 8 |
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