| Presentation | 2000/5/18 A Fiber-Optic Sensing System Developed for Detection of Isozyme of Cytochrome P450 and its Practical Performance K. Yoshida, H. Nagaushi, I. Sasaki, Y-B. Shen, Homei Kyo, Y. Hinata, A. Kazusaka, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | This report presents a fiber-optic sensing system developed for detection of isozymes reactions in living bodies. The fiber sensor consists of two of plastic optical fiber ; one is for delivery the optical power into a living body to excite fluorescent material that may indicate the metabolic activity of particular isozyme of cytochromeP450 and the other one for guiding fluorescent light to an optical detector. In order to confirm the system performance, isozyme of cytochrome P450 was induced in liver of living rats by giving toxicants generally known as environmental pollutants. The results we obtained show that isozymes of cytocromeP450 can be successfully detected through the fiber-optic sensing system. This implies that environmetal pollutants may be detecable through the combination of the biosensing system and the fiber-optic system. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Optical fiber sensor / fiber-optic sensor plastic fiber / cytochrome P450 / Enzyme / Isozyme |
| Paper # | OFT2000-8 |
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| Conference Information | |
| Committee | OFT |
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| Conference Date | 2000/5/18(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | |
| Vice Chair | |
| Secretary | |
| Assistant | |
| Paper Information | |
| Registration To | Optical Fiber Technology (OFT) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | A Fiber-Optic Sensing System Developed for Detection of Isozyme of Cytochrome P450 and its Practical Performance |
| Sub Title (in English) | |
| Keyword(1) | Optical fiber sensor |
| Keyword(2) | fiber-optic sensor plastic fiber |
| Keyword(3) | cytochrome P450 |
| Keyword(4) | Enzyme |
| Keyword(5) | Isozyme |
| 1st Author's Name | K. Yoshida |
| 1st Author's Affiliation | Hokkaido Institute of Technology() |
| 2nd Author's Name | H. Nagaushi |
| 2nd Author's Affiliation | Hokkaido Institute of Technology |
| 3rd Author's Name | I. Sasaki |
| 3rd Author's Affiliation | Hokkaido Institute of Technology |
| 4th Author's Name | Y-B. Shen |
| 4th Author's Affiliation | Advanced Technology Inc. |
| 5th Author's Name | Homei Kyo |
| 5th Author's Affiliation | A-tic |
| 6th Author's Name | Y. Hinata |
| 6th Author's Affiliation | A-tic |
| 7th Author's Name | A. Kazusaka |
| 7th Author's Affiliation | Hokkaido University |
| Date | 2000/5/18 |
| Paper # | OFT2000-8 |
| Volume (vol) | vol.100 |
| Number (no) | 84 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |