| Presentation | 2002/9/12 The Genotype Analysis with Clustering : Automatic Classification of Genotype Yoko HIGASHI, Arata SATO, Hirotaka HIGUCHI, Hitoshi SAKANO, Toshihiko MORIMOTO, Tsutomu MATSUNAGA, Keisuke ISHII, Masaaki MURAMATSU, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We suggest a method of clustering to label each individual the genotype. Since SNP, one of the nucleotide polymorphisms, is usually measured in the assay employing the fluorescent dyes, the individual SNP genotype is quantified as the luminescence intensity. Until now each individual SNP genotype, "A/A"," A/G","G/G", has been manually reviewed. As the laboratory staffs need to look at the plots and manually review each genotype, it is a big bottleneck for genotype analysis. In order to automate this procedure we developed a method of clustering by K-means and estimating the number of the clusters employing F-ratio as an index. We show the method and its effectiveness here. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | SNP genotype analysis / K-means / F-ratio |
| Paper # | WIT2002-14 |
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| Conference Information | |
| Committee | WIT |
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| Conference Date | 2002/9/12(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
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| Vice Chair | |
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| Paper Information | |
| Registration To | Well-being Information Technology(WIT) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | The Genotype Analysis with Clustering : Automatic Classification of Genotype |
| Sub Title (in English) | |
| Keyword(1) | SNP genotype analysis |
| Keyword(2) | K-means |
| Keyword(3) | F-ratio |
| 1st Author's Name | Yoko HIGASHI |
| 1st Author's Affiliation | R&D Headquarters NTT DATA Corporation() |
| 2nd Author's Name | Arata SATO |
| 2nd Author's Affiliation | HuBit Genomix |
| 3rd Author's Name | Hirotaka HIGUCHI |
| 3rd Author's Affiliation | HuBit Genomix |
| 4th Author's Name | Hitoshi SAKANO |
| 4th Author's Affiliation | HuBit Genomix |
| 5th Author's Name | Toshihiko MORIMOTO |
| 5th Author's Affiliation | HuBit Genomix |
| 6th Author's Name | Tsutomu MATSUNAGA |
| 6th Author's Affiliation | HuBit Genomix |
| 7th Author's Name | Keisuke ISHII |
| 7th Author's Affiliation | HuBit Genomix |
| 8th Author's Name | Masaaki MURAMATSU |
| 8th Author's Affiliation | HuBit Genomix |
| Date | 2002/9/12 |
| Paper # | WIT2002-14 |
| Volume (vol) | vol.102 |
| Number (no) | 319 |
| Page | pp.pp.- |
| #Pages | 4 |
| Date of Issue | |