Presentation 2002/10/18
Brain Regions for Word Retrieval and Speech Production, and Impact of Aging
Itaru TATSUMI, TAKAO FUSHIMI, NAOKO SAKUMA, Michio SENDA, Kenji ISHII, Masahiro MISHINA, Masashi OYAMA, Hinako TOYAMA, Keiichi ODA, Masayuki TANAKA, Yasuyuki GONDO,
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Abstract(in English) A PET activation study was conducted to young and elderly subjects to elucidate mechanisms of word finding difficulty in elderly people. Scans were made while the subjects were speaking aloud as many words in specified semantic or phonemic categories as possible. In the young subjects, the left anterior temporal lobe and the frontal pole were activated in the proper-noun fluency task, whereas the left infero-posterior temporal and frontal regions were activated in the remaining semantic (animate and inanimate) and syllable fluency tasks. The elderly subjects revealed different activation patterns from those of the young subjects : some areas were common in the both groups and others were not. In addition, the bilateral cerebellum, which was silent in the young subjects, was active in the syllable fluency task. This was considered as activity to compensate for deficient word retrieval in the elderly.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) verbal fluency / proper noun / animate / inanimate / syllable / speech production / PET / aging
Paper # TL2002-31
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Committee TL
Conference Date 2002/10/18(1days)
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Registration To Thought and Language (TL)
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Brain Regions for Word Retrieval and Speech Production, and Impact of Aging
Sub Title (in English)
Keyword(1) verbal fluency
Keyword(2) proper noun
Keyword(3) animate
Keyword(4) inanimate
Keyword(5) syllable
Keyword(6) speech production
Keyword(7) PET
Keyword(8) aging
1st Author's Name Itaru TATSUMI
1st Author's Affiliation Tokyo Metropolitan Institute of Gerontology()
2nd Author's Name TAKAO FUSHIMI
2nd Author's Affiliation Tokyo Metropolitan Institute of Gerontology
3rd Author's Name NAOKO SAKUMA
3rd Author's Affiliation Tokyo Metropolitan Institute of Gerontology
4th Author's Name Michio SENDA
4th Author's Affiliation Institute of Biomedical Research & Innovation
5th Author's Name Kenji ISHII
5th Author's Affiliation Tokyo Metropolitan Institute of Gerontology
6th Author's Name Masahiro MISHINA
6th Author's Affiliation Nippon Medical School
7th Author's Name Masashi OYAMA
7th Author's Affiliation Nippon Medical School
8th Author's Name Hinako TOYAMA
8th Author's Affiliation National Institute of Radiological Sciences
9th Author's Name Keiichi ODA
9th Author's Affiliation Tokyo Metropolitan Institute of Gerontology
10th Author's Name Masayuki TANAKA
10th Author's Affiliation Primate Research Institute, Kyoto University
11th Author's Name Yasuyuki GONDO
11th Author's Affiliation Tokyo Metropolitan Institute of Gerontology
Date 2002/10/18
Paper # TL2002-31
Volume (vol) vol.102
Number (no) 412
Page pp.pp.-
#Pages 6
Date of Issue