| Presentation | 2002/10/18 Functional and structural brain abnormalities underlying dysfunction of auditory language processing in schizophrenia Kiyoto KASAI, Kenji ITOH, Ichiro KOSHIDA, Masato YUMOTO, Akira IWANAMI, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Schizophrenia is associated with language-related cognitive dysfunction. Using high-resolution EEG and MEG, we demonstrated impaired frontotemporal cortical networks for automatic change detection of speech sounds in schizophrenia. Moreover, we found significantly smaller gray matter volume of left posterior superior temporal gyrus in first-episode patients with schizophrenia as compared with first-episode patients with affective psychosis and healthy subjects, which also significantly decreased over 1.5 years following onset. The language-related dysfunction in schizophrenia may be present at the early stage of auditory processing in the auditory cortex, and not just at stages involving higher-order semantic processes. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Schizophrenia / language / auditory / phoneme / superior temporal gyrus |
| Paper # | TL2002-28 |
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| Conference Information | |
| Committee | TL |
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| Conference Date | 2002/10/18(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
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| Paper Information | |
| Registration To | Thought and Language (TL) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Functional and structural brain abnormalities underlying dysfunction of auditory language processing in schizophrenia |
| Sub Title (in English) | |
| Keyword(1) | Schizophrenia |
| Keyword(2) | language |
| Keyword(3) | auditory |
| Keyword(4) | phoneme |
| Keyword(5) | superior temporal gyrus |
| 1st Author's Name | Kiyoto KASAI |
| 1st Author's Affiliation | Department of Neuropsychiatry, University of Tokyo() |
| 2nd Author's Name | Kenji ITOH |
| 2nd Author's Affiliation | Department of Cognitive and Speech Science, University of Tokyo |
| 3rd Author's Name | Ichiro KOSHIDA |
| 3rd Author's Affiliation | Department of Information Technology, Tokyo Engineering University |
| 4th Author's Name | Masato YUMOTO |
| 4th Author's Affiliation | Department of Laboratory Medicine, University of Tokyo |
| 5th Author's Name | Akira IWANAMI |
| 5th Author's Affiliation | Department of Neuropsychiatry, University of Tokyo |
| Date | 2002/10/18 |
| Paper # | TL2002-28 |
| Volume (vol) | vol.102 |
| Number (no) | 412 |
| Page | pp.pp.- |
| #Pages | 3 |
| Date of Issue | |