Presentation | 2004/3/10 Influence of Dendritic Spine Morphology on Temporal Change of Calcium / Calmoduline-Dependent Protein Kinase Density Shuichi KATO, Seiichi SAKATANI, Akira HIROSE, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | There are three types of spines in CAl hippocampus pyramidal cells i.e., mushroom,thin and stubby types. We calculate concentration of chemical materials such as Ca^<2+> and CaMKII - CaMCa_4 in spines. As a result, We find that the CaMKII - CaMCa_4's concentration in the mushroom type spine is higher than those of other spines. If input concentration of Ca^<2+> increases, CaMKII - CaMCa_4's concentration in mushroom type spine largely increase nonlineerly. Moreover the decay of CaMKII - CaMCa_4's concentration in mushroom type is several times slower than other types. This result is consistent with physiological experimental results. This analysis result elucidates one of the memory dynamics. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | CaMKII / CaM / LTP / spine / morphology / CA1 / hippocampus / Ca^<2+> |
Paper # | NC2003-137 |
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Conference Information | |
Committee | NC |
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Conference Date | 2004/3/10(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | Neurocomputing (NC) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Influence of Dendritic Spine Morphology on Temporal Change of Calcium / Calmoduline-Dependent Protein Kinase Density |
Sub Title (in English) | |
Keyword(1) | CaMKII |
Keyword(2) | CaM |
Keyword(3) | LTP |
Keyword(4) | spine |
Keyword(5) | morphology |
Keyword(6) | CA1 |
Keyword(7) | hippocampus |
Keyword(8) | Ca^<2+> |
1st Author's Name | Shuichi KATO |
1st Author's Affiliation | Dept. of Frontier Informatics, The University of Tokyo() |
2nd Author's Name | Seiichi SAKATANI |
2nd Author's Affiliation | Dept. of Frontier Informatics, The University of Tokyo |
3rd Author's Name | Akira HIROSE |
3rd Author's Affiliation | Dept. of Frontier Informatics, The University of Tokyo |
Date | 2004/3/10 |
Paper # | NC2003-137 |
Volume (vol) | vol.103 |
Number (no) | 732 |
Page | pp.pp.- |
#Pages | 6 |
Date of Issue |