| Presentation | 2004/3/10 Influence of Dendritic Spine Morphology on Temporal Change of Calcium / Calmoduline-Dependent Protein Kinase Density Shuichi KATO, Seiichi SAKATANI, Akira HIROSE, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | There are three types of spines in CAl hippocampus pyramidal cells i.e., mushroom,thin and stubby types. We calculate concentration of chemical materials such as Ca^<2+> and CaMKII - CaMCa_4 in spines. As a result, We find that the CaMKII - CaMCa_4's concentration in the mushroom type spine is higher than those of other spines. If input concentration of Ca^<2+> increases, CaMKII - CaMCa_4's concentration in mushroom type spine largely increase nonlineerly. Moreover the decay of CaMKII - CaMCa_4's concentration in mushroom type is several times slower than other types. This result is consistent with physiological experimental results. This analysis result elucidates one of the memory dynamics. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | CaMKII / CaM / LTP / spine / morphology / CA1 / hippocampus / Ca^<2+> |
| Paper # | NC2003-137 |
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| Conference Information | |
| Committee | NC |
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| Conference Date | 2004/3/10(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Influence of Dendritic Spine Morphology on Temporal Change of Calcium / Calmoduline-Dependent Protein Kinase Density |
| Sub Title (in English) | |
| Keyword(1) | CaMKII |
| Keyword(2) | CaM |
| Keyword(3) | LTP |
| Keyword(4) | spine |
| Keyword(5) | morphology |
| Keyword(6) | CA1 |
| Keyword(7) | hippocampus |
| Keyword(8) | Ca^<2+> |
| 1st Author's Name | Shuichi KATO |
| 1st Author's Affiliation | Dept. of Frontier Informatics, The University of Tokyo() |
| 2nd Author's Name | Seiichi SAKATANI |
| 2nd Author's Affiliation | Dept. of Frontier Informatics, The University of Tokyo |
| 3rd Author's Name | Akira HIROSE |
| 3rd Author's Affiliation | Dept. of Frontier Informatics, The University of Tokyo |
| Date | 2004/3/10 |
| Paper # | NC2003-137 |
| Volume (vol) | vol.103 |
| Number (no) | 732 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |