Presentation | 2004/3/10 The relation between Ca^<2+> influx and the magnitude of STDP in the hippocampal neural network Yasutoshi Kashiwagi, Yoichi Avil, Hidenori Watanabe, Takeshi Aihara, Minoru Tsukada, |
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Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | In the hippocampal CA1 area, repetitive correlated spiking of pre- and postsynaptic neurons can induce LTP and LTD , depending on the timing of the pre- and postsynaptic excitation(Spike timing Dependent Plasticity). While, it is shown that LTP and LTD are triggered depending on the level of postsynaptic intracellular calcium concentration. In this study , Ca^<2+> influx induced by the protocol of timing between pre- and postsynaptic excitation were spatially investigated by using the calcium imaging method in the hippocampal CA1 area. We analized the dynamics of calcium influx during repetitive stimulus and discussed the relatio between the dynamics and themaghifaile of STDP that the magnitude of LTP and LTD closely related to the velocity of calcium influx during repetitive stimulus. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | hippocampus / Ca<2+> / STDP / LTP LTD |
Paper # | NC2003-135 |
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Conference Information | |
Committee | NC |
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Conference Date | 2004/3/10(1days) |
Place (in Japanese) | (See Japanese page) |
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Topics (in Japanese) | (See Japanese page) |
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Paper Information | |
Registration To | Neurocomputing (NC) |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | The relation between Ca^<2+> influx and the magnitude of STDP in the hippocampal neural network |
Sub Title (in English) | |
Keyword(1) | hippocampus |
Keyword(2) | Ca<2+> |
Keyword(3) | STDP |
Keyword(4) | LTP LTD |
1st Author's Name | Yasutoshi Kashiwagi |
1st Author's Affiliation | Tamagawa University() |
2nd Author's Name | Yoichi Avil |
2nd Author's Affiliation | Tamagawa University |
3rd Author's Name | Hidenori Watanabe |
3rd Author's Affiliation | Tamagawa University |
4th Author's Name | Takeshi Aihara |
4th Author's Affiliation | Tamagawa University |
5th Author's Name | Minoru Tsukada |
5th Author's Affiliation | Tamagawa University |
Date | 2004/3/10 |
Paper # | NC2003-135 |
Volume (vol) | vol.103 |
Number (no) | 732 |
Page | pp.pp.- |
#Pages | 4 |
Date of Issue |