| Presentation | 2003/3/10 Participation of inhibitory input for synaptic plasticity via correlated pre- and postsynaptic activity Tatsuo KITAJIMA, Kazunobu TOGASHI, Makoto NISHIYAMA, Ken-ichi HARA, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | It has been demonstrated that correlated pre- and postsynaptic activity can induce either LTP or LTD, depending on the precise timing of pre- and postsynaptic activity, and a time window for LTP that exists on the activated pathway is flanked by two time windows for LTD and contribution of inhibitory synaptic inputs to this Mexican-hat type synaptic plasticity is suggested. In this paper a model neuron with soma, dendrite and spine is used in computer simulations to examine the Mexican-hat type time window during which the pairing of EPSPs and action potentials can produce such synaptic modifications. Computer simulations show that feedback and feedforward GABAergic inputs contribute not only to the regulate the polarity of synaptic modifications according to pattern of postsynaptic Ca^<2+> concentration via the interval between pre- and postsynaptic activity. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Mexican-hat type synaptic plasticity / Integrated synaptic learning rule / LTP / LTD time window / Backpropagated action potential |
| Paper # | NC2002-135 |
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| Conference Information | |
| Committee | NC |
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| Conference Date | 2003/3/10(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Participation of inhibitory input for synaptic plasticity via correlated pre- and postsynaptic activity |
| Sub Title (in English) | |
| Keyword(1) | Mexican-hat type synaptic plasticity |
| Keyword(2) | Integrated synaptic learning rule |
| Keyword(3) | LTP |
| Keyword(4) | LTD time window |
| Keyword(5) | Backpropagated action potential |
| 1st Author's Name | Tatsuo KITAJIMA |
| 1st Author's Affiliation | Faculty of Engineering, Yamagata University() |
| 2nd Author's Name | Kazunobu TOGASHI |
| 2nd Author's Affiliation | Faculty of Engineering, Yamagata University |
| 3rd Author's Name | Makoto NISHIYAMA |
| 3rd Author's Affiliation | School of Medicine, New York University School of Medicine |
| 4th Author's Name | Ken-ichi HARA |
| 4th Author's Affiliation | Faculty of Science and Engineering, Ishinomaki Sensyu University |
| Date | 2003/3/10 |
| Paper # | NC2002-135 |
| Volume (vol) | vol.102 |
| Number (no) | 729 |
| Page | pp.pp.- |
| #Pages | 5 |
| Date of Issue | |