| Presentation | 2002/12/6 A Model of Transmitter Release in the Synaptic Terminals of Retinal Bipolar Cells Tomokatsu KAWAKITA, Akito ISHIHARA, Shiro USUI, Masao TACHIBANA, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Retinal bipolar cells, which show a graded response to light stimulation, release glutamate as the transmitter phasically and tonically, and transmit the visual signal continuously to postsynaptic neurons. We constructed a mathematical model of glutamate release from bipolar cells by integrating the various physiological data. This model could simulate the voltage- and calcium-dependence of glutamate release. A simulation experiment revealed that the slow component of glutamate release was delayed by introduction of exogenous calcium buffer into the cell. This result suggests that the slow component contributes to the bell-shaped relationship between glutamate release and membrane potential. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Mathematical Model / Retinal Bipolar Cell / Synaptic Terminal / Transmitter Release |
| Paper # | NC2002-93 |
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| Committee | NC |
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| Conference Date | 2002/12/6(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Neurocomputing (NC) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | A Model of Transmitter Release in the Synaptic Terminals of Retinal Bipolar Cells |
| Sub Title (in English) | |
| Keyword(1) | Mathematical Model |
| Keyword(2) | Retinal Bipolar Cell |
| Keyword(3) | Synaptic Terminal |
| Keyword(4) | Transmitter Release |
| 1st Author's Name | Tomokatsu KAWAKITA |
| 1st Author's Affiliation | Department of Information & Computer Sciences, Toyohashi University of Technology() |
| 2nd Author's Name | Akito ISHIHARA |
| 2nd Author's Affiliation | Department of Information & Computer Sciences, Toyohashi University of Technology |
| 3rd Author's Name | Shiro USUI |
| 3rd Author's Affiliation | Department of Information & Computer Sciences, Toyohashi University of Technology |
| 4th Author's Name | Masao TACHIBANA |
| 4th Author's Affiliation | Department of Psychology, Graduate School of Humanities & Sociology, University of Tokyo |
| Date | 2002/12/6 |
| Paper # | NC2002-93 |
| Volume (vol) | vol.102 |
| Number (no) | 508 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |