| Presentation | 2004-06-17 Astrocytic [Ca^<2+>]i responses via IP_3 receptor type1 stimulated by glutamate at tripartite synapse Isao Goto, Kiyohisa Natsume, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Recently the participation of glial cells to neuronal information processing had been suggested. A kind of glial cells, astrocytes possess metabotropic glutamate receptor, so that the involvement of glial cells in neuronal information processing in brain can be considered. In the present paper, using our PLC8 model that is the model on the astrocytic intracellular Ca^<2+> concentration ([Ca^<2+>]i) oscillation involving type 1 IP3 receptor, we investigated astrocytic [Ca^<2+>]i responses by the various patterns of glutamate (Glu) stimulation. Quasi-periodic responses and chaotic responses were observed and caused by the repetitive stimulation of Glu. These results suggested that astrocytic [Ca^<2+>]i responses are modulated by the firing patterns of the neurons. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Tripartite synapse / Type 1 IP_3 receptor / Astrocyte / Intracellular Ca^<2+> spike |
| Paper # | NLP2004-22 |
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| Conference Information | |
| Committee | NLP |
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| Conference Date | 2004/6/10(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Nonlinear Problems (NLP) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Astrocytic [Ca^<2+>]i responses via IP_3 receptor type1 stimulated by glutamate at tripartite synapse |
| Sub Title (in English) | |
| Keyword(1) | Tripartite synapse |
| Keyword(2) | Type 1 IP_3 receptor |
| Keyword(3) | Astrocyte |
| Keyword(4) | Intracellular Ca^<2+> spike |
| 1st Author's Name | Isao Goto |
| 1st Author's Affiliation | Grad Sch Life Sci and Sys Eng, Kyushu Inst Tech() |
| 2nd Author's Name | Kiyohisa Natsume |
| 2nd Author's Affiliation | Grad Sch Life Sci and Sys Eng, Kyushu Inst Tech |
| Date | 2004-06-17 |
| Paper # | NLP2004-22 |
| Volume (vol) | vol.104 |
| Number (no) | 112 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |