| Presentation | 2003/11/14 Neurosteroid modulates ethanol-induced suppression of long-term potontiation in the CA1 region of the hippocampus Chikoo OOSAWA, Shinsaku SHIROMA, Kaoru KOMETANI, |
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| PDF Download Page | PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Effects of ethanol (25mM) and dehydroepiandrosterone sulfate (DHEAS;25uM) On the long-term potentiatiOn (LTP) were investigated in area CA1 of the hippocampus. When EtOH and DHEAS were co-administered, both the magnitude of LTP and the amplitude of NMoA receptor mediated EPSP (NMDA-pEPSP) were reduced to those in the presence of EtOH. When DHEAS was applied first and then EtOH and DHEAS were co-administered, both magnitude of LTP and the amplitude of NMDA-pEPSP were increased to those in the presence of DHEAS. These results were consistent with effects of the two drugs on the glycine site of the NMDA receptor. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | hippocampus / long-term potentiation / neurosteroid / ethanol |
| Paper # | NLP2003-109 |
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| Conference Information | |
| Committee | NLP |
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| Conference Date | 2003/11/14(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Nonlinear Problems (NLP) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Neurosteroid modulates ethanol-induced suppression of long-term potontiation in the CA1 region of the hippocampus |
| Sub Title (in English) | |
| Keyword(1) | hippocampus |
| Keyword(2) | long-term potentiation |
| Keyword(3) | neurosteroid |
| Keyword(4) | ethanol |
| 1st Author's Name | Chikoo OOSAWA |
| 1st Author's Affiliation | Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology() |
| 2nd Author's Name | Shinsaku SHIROMA |
| 2nd Author's Affiliation | Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology |
| 3rd Author's Name | Kaoru KOMETANI |
| 3rd Author's Affiliation | Faculty of Computer Science and Systems Engineering, Kyushu Institute of Technology |
| Date | 2003/11/14 |
| Paper # | NLP2003-109 |
| Volume (vol) | vol.103 |
| Number (no) | 463 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |