Presentation 2004/1/13
Evaluation of mutagenicity of complex magnetic fields with static and time-vary ing components.
Masateru IKEHATA, Tetsuya NAGAI, Yukihisa SUZUKI, Masao TAKI, Junji MIYAKOSHI, Takao KOANA,
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Abstract(in English) Mutagenicity of complex exposure to static magnetic field(MF) and 50Hz MF was investigated. We developed a exposure system that can generate a 5T static MF and a ImT 50Hz MF simultaneously without temperature fluctuation. To investigate the mutagenicity, bacterial mutation assay (Ames test) using Salmonella typhimurium TA98 and TA100, and also yeast mutation assay using Saccharomyces cerevisiae XD83 were performed. It was found that gene conversion/recombination frequency in S. cerevisiae XD83 was slightly increased by exposure to a complex MF while point mutation frequency in S. cerevisiae and S. typhimurium was not affected. Possible mechanism and evaluation of mutagenicity will be discussed.
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Keyword(in English) Complex magnetic field / Biological effect / Mutation assay / Bacteria / Yeast / Safety estimation
Paper # EMCJ2003-136
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Committee EMCJ
Conference Date 2004/1/13(1days)
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Registration To Electromagnetic Compatibility (EMCJ)
Language JPN
Title (in Japanese) (See Japanese page)
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Title (in English) Evaluation of mutagenicity of complex magnetic fields with static and time-vary ing components.
Sub Title (in English)
Keyword(1) Complex magnetic field
Keyword(2) Biological effect
Keyword(3) Mutation assay
Keyword(4) Bacteria
Keyword(5) Yeast
Keyword(6) Safety estimation
1st Author's Name Masateru IKEHATA
1st Author's Affiliation Environmental Engineering Division, Railway Technical Research Institute()
2nd Author's Name Tetsuya NAGAI
2nd Author's Affiliation Department of Electrical Engineering, Graduate School of Engineering , Tokyo Metropolitan University
3rd Author's Name Yukihisa SUZUKI
3rd Author's Affiliation Department of Electrical Engineering, Graduate School of Engineering , Tokyo Metropolitan University
4th Author's Name Masao TAKI
4th Author's Affiliation Department of Electrical Engineering, Graduate School of Engineering , Tokyo Metropolitan University
5th Author's Name Junji MIYAKOSHI
5th Author's Affiliation Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, Hirosaki University
6th Author's Name Takao KOANA
6th Author's Affiliation Low Dose Radiation Research Center, Central Research Institute of Electrical Power Industry
Date 2004/1/13
Paper # EMCJ2003-136
Volume (vol) vol.103
Number (no) 564
Page pp.pp.-
#Pages 4
Date of Issue