| Presentation | 2004-09-14 The Determination of Molecular Structures by the Optimization with a Gaussian Objective Function Ryoji USUI, Shinji DOI, Sadatoshi KUMAGAI, |
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| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | It is important to determine a three-dimensional protein structure in the elucidation of biological phenomena, the development of drug medicines, etc. The conformations of proteins are mainly analyzed by the NMR (Nuclear Magnetic Resonance) spectroscopy and the X-ray crystallography. In the NMR spectroscopy, distance data among some atoms are approximately given, and a protein structure is determined by solving the so-called distance geometry problem. In this research, we propose a gaussian objective function and determine the protein conformation by solving the global optimization problem of the objective function. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | protein / conformation / distance geometry problem / gaussian objective function / global optimization |
| Paper # | CAS2004-33,NLP2004-45 |
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| Conference Information | |
| Committee | CAS |
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| Conference Date | 2004/9/7(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
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| Paper Information | |
| Registration To | Circuits and Systems (CAS) |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | The Determination of Molecular Structures by the Optimization with a Gaussian Objective Function |
| Sub Title (in English) | |
| Keyword(1) | protein |
| Keyword(2) | conformation |
| Keyword(3) | distance geometry problem |
| Keyword(4) | gaussian objective function |
| Keyword(5) | global optimization |
| 1st Author's Name | Ryoji USUI |
| 1st Author's Affiliation | Osaka University Graduate School() |
| 2nd Author's Name | Shinji DOI |
| 2nd Author's Affiliation | Osaka University Graduate School |
| 3rd Author's Name | Sadatoshi KUMAGAI |
| 3rd Author's Affiliation | Osaka University Graduate School |
| Date | 2004-09-14 |
| Paper # | CAS2004-33,NLP2004-45 |
| Volume (vol) | vol.104 |
| Number (no) | 293 |
| Page | pp.pp.- |
| #Pages | 6 |
| Date of Issue | |