Presentation 2002/10/18
On Creating Reference Maps for Evaluation of Ultrasound Images of Carotid Plaque
Jens E WILHJELM, Maja S JENSEN, Kim L GAMMELMARK, Birgitte SAHL, Kjeld MARTINSEN, Jon HANSEN, Talo BRANDT, Soren K JESPERSEN, Erling FALK, Henrik SILLESEN,
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Abstract(in English) For the purpose of developing ultrasonic tissue classification methods, this work investigates a method to create reference maps of biological tissue. Specifically, formalin fixed carotid atherosclerotic plaque was molded into an agar block containing at set of fiducial markers. The block was scanned with spatial compound ultrasound at 7.5 MHz. Both tissue and fiducial markers were imaged. The block was afterwards sliced at the location of the fiducial markers. The slices were then photographed and analyzed histologically. From this data, reference maps with the same geometry as the ultrasound images were created. For each pixel in the ultrasound image, these reference maps indicate tissue type, such as collagen poor tissue, collagen rich tissue, etc. Because the histological method could not identify calcification with certainty, alternative methods (e.g. X-ray) had to be included to ensure proper identification of calcification.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Spatial compounding / histology / formalin fixation / tissue classification
Paper # UC2002-63
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Committee US
Conference Date 2002/10/18(1days)
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Registration To Ultrasonics (US)
Language ENG
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) On Creating Reference Maps for Evaluation of Ultrasound Images of Carotid Plaque
Sub Title (in English)
Keyword(1) Spatial compounding
Keyword(2) histology
Keyword(3) formalin fixation
Keyword(4) tissue classification
1st Author's Name Jens E WILHJELM
1st Author's Affiliation Orsted・DTU, Technical University of Denmark()
2nd Author's Name Maja S JENSEN
2nd Author's Affiliation Orsted・DTU, Technical University of Denmark
3rd Author's Name Kim L GAMMELMARK
3rd Author's Affiliation Orsted・DTU, Technical University of Denmark
4th Author's Name Birgitte SAHL
4th Author's Affiliation Institute of Experimental Clinical Research, Aarhus University Hospital (Skejby)
5th Author's Name Kjeld MARTINSEN
5th Author's Affiliation Orsted・DTU, Technical University of Denmark
6th Author's Name Jon HANSEN
6th Author's Affiliation Novo Nordisk A/S, Brennum Park
7th Author's Name Talo BRANDT
7th Author's Affiliation Orsted・DTU, Technical University of Denmark
8th Author's Name Soren K JESPERSEN
8th Author's Affiliation Novo Nordisk A/S, Brennum Park
9th Author's Name Erling FALK
9th Author's Affiliation Institute of Experimental Clinical Research, Aarhus University Hospital (Skejby)
10th Author's Name Henrik SILLESEN
10th Author's Affiliation Dept. of Vascular Surgery, Gentofte University Hospital
Date 2002/10/18
Paper # UC2002-63
Volume (vol) vol.102
Number (no) 411
Page pp.pp.-
#Pages 5
Date of Issue