| Presentation | 2018-11-22 Electrochemical impedance property of implantable porous electrode during short-term in vivo stimulation for visual prosthesis with suprachoroidal transretinal stimulation Shuhei Nomura, Hiroyuki Tashiro, Yasuo Terasawa, Jun Ohta, |
|---|---|
| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Visual prothesis is a medical device that restores lost visual function by electrical stimulation to the visual nervous system via implanted metal electrodes. Excessive and chronic stimulation causes damage to the surrounding tissue and to the electrodes. In this study, we evaluated the effect of stimulation current on the electrochemical characteristics of the electrodes implanted in a living body. We implanted a porous electrode array in a rabbit’s eyeball, and evaluated electrochemical impedance of active and inactive electrodes over a month. The electrochemical characteristics of the electrodes differed between active and inactive electrode. Increase of solution resistances of the inactive electrode was observed over 3 weeks after implantation. It was considered to be caused by capsulation due to foreign-body reaction. On the other hand, the similar change was not observed in the active electrode. It might be owing to desorption of adsorbed protein from the surface of the electrode by the stimulation current. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Visual prosthesis / Stimulation electrode / Electrochemical impedance spectroscopy / Equivalent circuit analysis |
| Paper # | MBE2018-47 |
| Date of Issue | 2018-11-15 (MBE) |
| Conference Information | |
| Committee | MBE / NC |
|---|---|
| Conference Date | 2018/11/22(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | Masaki Kyoso(TCU) / Yutaka Hirata(Chubu Univ.) |
| Vice Chair | Taishin Nomura(Osaka Univ.) / Hayaru Shouno(UEC) |
| Secretary | Taishin Nomura(Kindai Univ.) / Hayaru Shouno(Nagoya Univ.) |
| Assistant | Takumi Kobayashi(YNU) / Ｙａｓｕｙｕｋｉ Ｓｕｚｕｋｉ(Osaka Univ.) / Keiichiro Inagaki(Chubu Univ.) / Takashi Shinozaki(NICT) |
| Paper Information | |
| Registration To | Technical Committee on ME and Bio Cybernetics / Technical Committee on Neurocomputing |
|---|---|
| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Electrochemical impedance property of implantable porous electrode during short-term in vivo stimulation for visual prosthesis with suprachoroidal transretinal stimulation |
| Sub Title (in English) | |
| Keyword(1) | Visual prosthesis |
| Keyword(2) | Stimulation electrode |
| Keyword(3) | Electrochemical impedance spectroscopy |
| Keyword(4) | Equivalent circuit analysis |
| 1st Author's Name | Shuhei Nomura |
| 1st Author's Affiliation | Teikyo University/Kyushu University(Teikyo Univ/Kyushu Univ) |
| 2nd Author's Name | Hiroyuki Tashiro |
| 2nd Author's Affiliation | Kyushu University(Kyushu Univ.) |
| 3rd Author's Name | Yasuo Terasawa |
| 3rd Author's Affiliation | NIDEK CO., LTD.(NIDEK) |
| 4th Author's Name | Jun Ohta |
| 4th Author's Affiliation | Nara Institute of Science and Technology(NAIST) |
| Date | 2018-11-22 |
| Paper # | MBE2018-47 |
| Volume (vol) | vol.118 |
| Number (no) | MBE-321 |
| Page | pp.pp.55-60(MBE), |
| #Pages | 6 |
| Date of Issue | 2018-11-15 (MBE) |