Presentation | 2018-10-19 Evaluation of the ambiguity in tilt-translation discrimination by using vestibulo-ocular reflex in goldfish Masanori Nakano, Yutaka Hirata, |
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PDF Download Page | PDF download Page Link |
Abstract(in Japanese) | (See Japanese page) |
Abstract(in English) | According to Einstein’s equivalence principle, the otolith organs, which is biological accelerometers in inner ears, cannot distinguish translational motion from tilt motion relative to gravity, and vice versa. This is called tilt-translation ambiguity. Humans can correctly perceive these two types of self-motion even in the dark without visual information. In theory, the tilt-translation ambiguity problem can be solved by a simple differential equation consisting of linear and gravitational accelerations and angular velocity (Angelaki et al., 1999). A previous study showed in monkeys that the cerebellum solves the tilt-translation discrimination problem as Purkinje cells code only translational acceleration information in response to combined tilt-translation stimulations (Yakusheva et al., 2007). However, it is still enigmatic as to how the cerebellar neuronal circuitry solves the tilt-translation ambiguity problem. Presently, as the first step for elucidating cerebellar neuronal mechanism to solve the problem, we investigated in goldfish the vestibulo-ocular reflex (VOR) in the dark elicited by tilt-translation combined stimulations as an indicator of their ability in discriminating tilt from translation. We demonstrate that in normal goldfish, different and proper VOR eye movements were observed during lateral translation and static roll tilt. By contrast, after cerebellectomy, similar VOR eye movements were observed during these different vestibular stimulations. The results suggest that 1) goldfish is a good model system to investigate neuronal mechanisms of the tilt-translation discrimination, and 2) the cerebellum plays a crucial role in solving the tilt-translation ambiguity problem in goldfish as in monkeys. |
Keyword(in Japanese) | (See Japanese page) |
Keyword(in English) | Cerebellum / Otolith / Vestibulo-ocular Reflex / Goldfish / Eye movement |
Paper # | NC2018-20 |
Date of Issue | 2018-10-12 (NC) |
Conference Information | |
Committee | NC / MBE |
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Conference Date | 2018/10/19(2days) |
Place (in Japanese) | (See Japanese page) |
Place (in English) | Tohoku Univ. |
Topics (in Japanese) | (See Japanese page) |
Topics (in English) | |
Chair | Yutaka Hirata(Chubu Univ.) / Masaki Kyoso(TCU) |
Vice Chair | Hayaru Shouno(UEC) / Taishin Nomura(Osaka Univ.) |
Secretary | Hayaru Shouno(Nagoya Univ.) / Taishin Nomura(NAIST) |
Assistant | Keiichiro Inagaki(Chubu Univ.) / Takashi Shinozaki(NICT) / Takumi Kobayashi(YNU) / Yasuyuki Suzuki(Osaka Univ.) |
Paper Information | |
Registration To | Technical Committee on Neurocomputing / Technical Committee on ME and Bio Cybernetics |
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Language | JPN |
Title (in Japanese) | (See Japanese page) |
Sub Title (in Japanese) | (See Japanese page) |
Title (in English) | Evaluation of the ambiguity in tilt-translation discrimination by using vestibulo-ocular reflex in goldfish |
Sub Title (in English) | |
Keyword(1) | Cerebellum |
Keyword(2) | Otolith |
Keyword(3) | Vestibulo-ocular Reflex |
Keyword(4) | Goldfish |
Keyword(5) | Eye movement |
1st Author's Name | Masanori Nakano |
1st Author's Affiliation | Chubu University(Chubu Univ.) |
2nd Author's Name | Yutaka Hirata |
2nd Author's Affiliation | Chubu University(Chubu Univ.) |
Date | 2018-10-19 |
Paper # | NC2018-20 |
Volume (vol) | vol.118 |
Number (no) | NC-258 |
Page | pp.pp.39-39(NC), |
#Pages | 1 |
Date of Issue | 2018-10-12 (NC) |