Presentation 2018-10-19
Evaluation of the ambiguity in tilt-translation discrimination by using vestibulo-ocular reflex in goldfish
Masanori Nakano, Yutaka Hirata,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) According to Einstein’s equivalence principle, the otolith organs, which is biological accelerometers in inner ears, cannot distinguish translational motion from tilt motion relative to gravity, and vice versa. This is called tilt-translation ambiguity. Humans can correctly perceive these two types of self-motion even in the dark without visual information. In theory, the tilt-translation ambiguity problem can be solved by a simple differential equation consisting of linear and gravitational accelerations and angular velocity (Angelaki et al., 1999). A previous study showed in monkeys that the cerebellum solves the tilt-translation discrimination problem as Purkinje cells code only translational acceleration information in response to combined tilt-translation stimulations (Yakusheva et al., 2007). However, it is still enigmatic as to how the cerebellar neuronal circuitry solves the tilt-translation ambiguity problem. Presently, as the first step for elucidating cerebellar neuronal mechanism to solve the problem, we investigated in goldfish the vestibulo-ocular reflex (VOR) in the dark elicited by tilt-translation combined stimulations as an indicator of their ability in discriminating tilt from translation. We demonstrate that in normal goldfish, different and proper VOR eye movements were observed during lateral translation and static roll tilt. By contrast, after cerebellectomy, similar VOR eye movements were observed during these different vestibular stimulations. The results suggest that 1) goldfish is a good model system to investigate neuronal mechanisms of the tilt-translation discrimination, and 2) the cerebellum plays a crucial role in solving the tilt-translation ambiguity problem in goldfish as in monkeys.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Cerebellum / Otolith / Vestibulo-ocular Reflex / Goldfish / Eye movement
Paper # NC2018-20
Date of Issue 2018-10-12 (NC)

Conference Information
Committee NC / MBE
Conference Date 2018/10/19(2days)
Place (in Japanese) (See Japanese page)
Place (in English) Tohoku Univ.
Topics (in Japanese) (See Japanese page)
Topics (in English)
Chair Yutaka Hirata(Chubu Univ.) / Masaki Kyoso(TCU)
Vice Chair Hayaru Shouno(UEC) / Taishin Nomura(Osaka Univ.)
Secretary Hayaru Shouno(Nagoya Univ.) / Taishin Nomura(NAIST)
Assistant Keiichiro Inagaki(Chubu Univ.) / Takashi Shinozaki(NICT) / Takumi Kobayashi(YNU) / Yasuyuki Suzuki(Osaka Univ.)

Paper Information
Registration To Technical Committee on Neurocomputing / Technical Committee on ME and Bio Cybernetics
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Evaluation of the ambiguity in tilt-translation discrimination by using vestibulo-ocular reflex in goldfish
Sub Title (in English)
Keyword(1) Cerebellum
Keyword(2) Otolith
Keyword(3) Vestibulo-ocular Reflex
Keyword(4) Goldfish
Keyword(5) Eye movement
1st Author's Name Masanori Nakano
1st Author's Affiliation Chubu University(Chubu Univ.)
2nd Author's Name Yutaka Hirata
2nd Author's Affiliation Chubu University(Chubu Univ.)
Date 2018-10-19
Paper # NC2018-20
Volume (vol) vol.118
Number (no) NC-258
Page pp.pp.39-39(NC),
#Pages 1
Date of Issue 2018-10-12 (NC)