Presentation 2018-09-06
A Study on Modeling of Peripheral Nerves in Nerve Response Analysis
Ryota Hayami, Takahiro Ito, Jose Gomez-Tamez, Wasaka Toshiaki, Akimasa Hirata,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) In recent years, there has been a growing interest in selective stimulation of various small fibers in the skin for pain research. Intra-epidermal Electric Stimulation (IES) has been proposed for selective stimulation by injecting a weak current through a concentric bipolar needle electrode. However, there are few studies on stimulation thresholds considered of safety. By constructing a computational model of peripheral nerve included pain sensation, it becomes possible to optimize electrodes and input current when IES is performed, and selective stimulation improvement can be expected. In this study, we examined effect of electrical parameters of the conventional nerve model on activation threshold of peripheral myelinated nerve (Aδ fiber). The potential distribution by IES is computed by electromagnetic field analysis, and a threshold value was searched using a neural model. Although it was possible to approximate computation results to experimental results of pain threshold by modifying the electrical parameters,computation results are compared with experimental results of pain threshold and showed a pain threshold prediction error of 90% with respect to experimental measurements. As a result, Modeling including pain sensation is difficult by only modifying the electrical parameters of the conventional myelinated nerve model, it seems necessary to consider the possibility that multiple nerves are reacting.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Peripheral nerve / Epidermal electrical stimulation / Pain threshold
Paper # EST2018-45
Date of Issue 2018-08-30 (EST)

Conference Information
Committee EST
Conference Date 2018/9/6(2days)
Place (in Japanese) (See Japanese page)
Place (in English) Kumejima-machi, Okinawa
Topics (in Japanese) (See Japanese page)
Topics (in English) Simulation techniques, etc.
Chair Akimasa Hirata(Nagoya Inst. of Tech.)
Vice Chair Shinichiro Ohnuki(Nihon Univ.) / Masayuki Kimishima(Advantest) / Jun Shibayama(Hosei Univ.)
Secretary Shinichiro Ohnuki(CIST) / Masayuki Kimishima(National Inst. of Tech.,Sendai College) / Jun Shibayama
Assistant Takahiro Ito(Nagoya Inst. of Tech.) / Kazuhiro Fujita(Fujitsu)

Paper Information
Registration To Technical Committee on Electronics Simulation Technology
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) A Study on Modeling of Peripheral Nerves in Nerve Response Analysis
Sub Title (in English)
Keyword(1) Peripheral nerve
Keyword(2) Epidermal electrical stimulation
Keyword(3) Pain threshold
1st Author's Name Ryota Hayami
1st Author's Affiliation Nagoya Insititute of Technology(NITech)
2nd Author's Name Takahiro Ito
2nd Author's Affiliation Nagoya Insititute of Technology(NITech)
3rd Author's Name Jose Gomez-Tamez
3rd Author's Affiliation Nagoya Insititute of Technology(NITech)
4th Author's Name Wasaka Toshiaki
4th Author's Affiliation Nagoya Insititute of Technology(NITech)
5th Author's Name Akimasa Hirata
5th Author's Affiliation Nagoya Insititute of Technology(NITech)
Date 2018-09-06
Paper # EST2018-45
Volume (vol) vol.118
Number (no) EST-209
Page pp.pp.17-21(EST),
#Pages 5
Date of Issue 2018-08-30 (EST)