| Presentation | 2018-07-24 Photodynamic Diagnosis for Malignant Pleural Diseases using 5-Aminolevulinic acid and Auto fluorescence Imaging System Masahiro Kitada, Yoshinobu Ohsaki, Shunsuke Yasuda, Nana Takahashi, Satoshi Okazaki, Kei Ishibashi, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We have developed a new diagnostic method using the photosensitizer 5-aminolevulinic acid (5ALA) for diagnosing intrathoracic malignant lesions. When ingested exogenously, 5ALA is metabolized to a heme precursor, protoporphyrin IX, which stays in malignant cells and emits red to pink luminescence of about 630 nm. Malignant lesions on the pleural surface emitted pink autofluorescence in contrast to the green autofluorescence of the surrounding normal tissues observed by an autofluorescence imaging system. This system achieved accurate localization of malignant lesions, suggesting that it may also be applicable to photodynamic therapy. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Malignant pleural disease, / Auto fluorescence / Photodynamic diagnosis / 5-Aminolevulnic acid（5ALA） |
| Paper # | MI2018-25 |
| Date of Issue | 2018-07-17 (MI) |
| Conference Information | |
| Committee | MI |
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| Conference Date | 2018/7/24(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | aiina (Morioka, Iwate) |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Medical Imaging, etc. |
| Chair | Kensaku Mori(Nagoya Univ.) |
| Vice Chair | Yoshiki Kawata(Tokushima Univ.) / Yuichi Kimura(Kinki Univ.) |
| Secretary | Yoshiki Kawata(Aichi Inst. of Tech.) / Yuichi Kimura(Nagoya Inst. of Tech.) |
| Assistant | Ryo Haraguchi(Univ. of Hyogo) / Yasushi Hirano(Yamaguchi Univ.) |
| Paper Information | |
| Registration To | Technical Committee on Medical Imaging |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Photodynamic Diagnosis for Malignant Pleural Diseases using 5-Aminolevulinic acid and Auto fluorescence Imaging System |
| Sub Title (in English) | |
| Keyword(1) | Malignant pleural disease, |
| Keyword(2) | Auto fluorescence |
| Keyword(3) | Photodynamic diagnosis |
| Keyword(4) | 5-Aminolevulnic acid（5ALA） |
| 1st Author's Name | Masahiro Kitada |
| 1st Author's Affiliation | Asahikawa Medical University(AMU) |
| 2nd Author's Name | Yoshinobu Ohsaki |
| 2nd Author's Affiliation | Asahikawa Medical University(AMU) |
| 3rd Author's Name | Shunsuke Yasuda |
| 3rd Author's Affiliation | Asahikawa Medical University(AMU) |
| 4th Author's Name | Nana Takahashi |
| 4th Author's Affiliation | Asahikawa Medical University(AMU) |
| 5th Author's Name | Satoshi Okazaki |
| 5th Author's Affiliation | Asahikawa Medical University(AMU) |
| 6th Author's Name | Kei Ishibashi |
| 6th Author's Affiliation | Asahikawa Medical University(AMU) |
| Date | 2018-07-24 |
| Paper # | MI2018-25 |
| Volume (vol) | vol.118 |
| Number (no) | MI-150 |
| Page | pp.pp.17-20(MI), |
| #Pages | 4 |
| Date of Issue | 2018-07-17 (MI) |