| Presentation | 2018-03-13 Extraction of Factor Genes by Comparing Sequence Mutations in Gene Regions Based on NGS Data Kazuma Matsui, Tomohiro Umezu, Junko H. Ohyashiki, Yutaka Fukuoka, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | In this study, a method was proposed for determining differential mutations in next generation sequencing datasets from multiple myeloma cell lines cultured under normal and hypoxic conditions. Many differential mutations were found around tumor suppressor genes, suggesting that those genes play a role in hypoxia tolerance. The obtained gene expression data was statistically processed to extract candidate disease factor genes. These results indicated the usefulness of the proposed method. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Next Generation Sequencer / mutation analysis / factor gene |
| Paper # | MBE2017-95 |
| Date of Issue | 2018-03-06 (MBE) |
| Conference Information | |
| Committee | MBE / NC |
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| Conference Date | 2018/3/13(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Kikai-Shinko-Kaikan Bldg. |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | ME, general |
| Chair | Kazuki Nakajima(Univ. of Toyama) / Masafumi Hagiwara(Keio Univ.) |
| Vice Chair | Masaki Kyoso(TCU) / Yutaka Hirata(Chubu Univ.) |
| Secretary | Masaki Kyoso(Toyama Pref. Univ.) / Yutaka Hirata(Kindai Univ.) |
| Assistant | Kim Juhyon(Univ. of Toyama) / Takumi Kobayashi(YNU) / Yoshihisa Shinozawa(Keio Univ.) / Keiichiro Inagaki(Chubu Univ.) |
| Paper Information | |
| Registration To | Technical Committee on ME and Bio Cybernetics / Technical Committee on Neurocomputing |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Extraction of Factor Genes by Comparing Sequence Mutations in Gene Regions Based on NGS Data |
| Sub Title (in English) | |
| Keyword(1) | Next Generation Sequencer |
| Keyword(2) | mutation analysis |
| Keyword(3) | factor gene |
| 1st Author's Name | Kazuma Matsui |
| 1st Author's Affiliation | Kogakuin University(Kogakuin Univ.) |
| 2nd Author's Name | Tomohiro Umezu |
| 2nd Author's Affiliation | Tokyo Medical University(Tokyo Medical Univ.) |
| 3rd Author's Name | Junko H. Ohyashiki |
| 3rd Author's Affiliation | Tokyo Medical University(Tokyo Medical Univ.) |
| 4th Author's Name | Yutaka Fukuoka |
| 4th Author's Affiliation | Kogakuin University(Kogakuin Univ.) |
| Date | 2018-03-13 |
| Paper # | MBE2017-95 |
| Volume (vol) | vol.117 |
| Number (no) | MBE-507 |
| Page | pp.pp.79-82(MBE), |
| #Pages | 4 |
| Date of Issue | 2018-03-06 (MBE) |