| Presentation | 2018-01-31 Liquid-Phase Detection of Biomaterial Using Magnetic Markers Yoshitsugu Takafuji, Kouta Irie, Kazuki Akiyoshi, Teruyoshi Sasayama, Takashi Yoshida, Keizi Enpuku, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | We have been developing a liquid-phase immunoassay using magnetic markers and a superconducting quantum interference device (SQUID). In this method, bound and free markers are magnetically differentiated by using the Brownian relaxation of the free markers. Hence, the time consuming washing process that is needed in the conventional optical method for Bound/Free (B/F) separation can be eliminated. Using the method, we demonstrated a detection of C-reactive protein (CRP). We obtained good correlation between the detected signal flux and the concentration of CRP. The minimum detectable concentration was 1 pg/mL. Since the present sensitivity is limited by the blank signal caused by the aggregation of free markers, much improvement will be possible if this problem is solved. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | CRP / Brownian Relaxation / Immunoassay / Magnetic Marker / HTS SQUID |
| Paper # | SCE2017-39 |
| Date of Issue | 2018-01-24 (SCE) |
| Conference Information | |
| Committee | SCE |
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| Conference Date | 2018/1/31(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Kikai-Shinko-Kaikan Bldg. |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | SQUID, high frequency, sensing technologies and their applications, etc. |
| Chair | Hiroaki Myoren(Saitama Univ.) |
| Vice Chair | |
| Secretary | (National Defense Academy) |
| Assistant | Hiroyuki Akaike(Daido Univ.) |
| Paper Information | |
| Registration To | Technical Committee on Superconductive Electronics |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Liquid-Phase Detection of Biomaterial Using Magnetic Markers |
| Sub Title (in English) | |
| Keyword(1) | CRP |
| Keyword(2) | Brownian Relaxation |
| Keyword(3) | Immunoassay |
| Keyword(4) | Magnetic Marker |
| Keyword(5) | HTS SQUID |
| 1st Author's Name | Yoshitsugu Takafuji |
| 1st Author's Affiliation | Kyushu University(Kyushu Univ.) |
| 2nd Author's Name | Kouta Irie |
| 2nd Author's Affiliation | Kyushu University(Kyushu Univ.) |
| 3rd Author's Name | Kazuki Akiyoshi |
| 3rd Author's Affiliation | Kyushu University(Kyushu Univ.) |
| 4th Author's Name | Teruyoshi Sasayama |
| 4th Author's Affiliation | Kyushu University(Kyushu Univ.) |
| 5th Author's Name | Takashi Yoshida |
| 5th Author's Affiliation | Kyushu University(Kyushu Univ.) |
| 6th Author's Name | Keizi Enpuku |
| 6th Author's Affiliation | Kyushu University(Kyushu Univ.) |
| Date | 2018-01-31 |
| Paper # | SCE2017-39 |
| Volume (vol) | vol.117 |
| Number (no) | SCE-428 |
| Page | pp.pp.45-50(SCE), |
| #Pages | 6 |
| Date of Issue | 2018-01-24 (SCE) |