| Presentation | 2017-10-07 Changes in light response characteristics of mouse retinal ganglion cells depending on background light Kenji Shiota, Yuki Naruto, Yuki Kashiwagi, Naofumi Suemats, Tetsuya Yagi, Yuki Hayashida, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | In recent years, the mouse has attracted attention as an experimental animal for studying retinal neuronal circuits. And it has been shown that the photosensitivity and the temporal filter characteristics of the photoresponse of the ganglion cells in the cone pathway are comparable to those of the primate retina. However, it is not fully understood how spike firing characteristics in response to step light stimulation of these output cells can change depending on the visual environment such as background light. In this study, we investigated by electrophysiological experiments whether spike firing response of mouse retinal ganglion cells can change according to the difference of two background light conditions between mesopic and photopic vision. In the experiments, time-series spike data were recorded from the isolated retina tissue using a planar multielectrode array. The single spike units were separated by the principal component analysis and cluster analysis, and then, were classified into different subtypes based on characteristics of the response to step light stimuli. As a result, in some subtypes, the photoresponse was disappeared by the adaptation from mesopic to photopic vision, but in other cases, a qualitative change in the response characteristics was not observed. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | mouse retinal ganglion cell / step light stimulus / background light / mesopic and photopic vision |
| Paper # | MBE2017-43 |
| Date of Issue | 2017-09-30 (MBE) |
| Conference Information | |
| Committee | MBE / NC |
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| Conference Date | 2017/10/7(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Osaka Electro-Communication University |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | ME, general |
| Chair | Kazuki Nakajima(Univ. of Toyama) / Masafumi Hagiwara(Keio Univ.) |
| Vice Chair | Masaki Kyoso(TCU) / Yutaka Hirata(Chubu Univ.) |
| Secretary | Masaki Kyoso(Toyama Pref. Univ.) / Yutaka Hirata(Kindai Univ.) |
| Assistant | Kim Juhyon(Univ. of Toyama) / Takumi Kobayashi(YNU) / Yoshihisa Shinozawa(Keio Univ.) / Keiichiro Inagaki(Chubu Univ.) |
| Paper Information | |
| Registration To | Technical Committee on ME and Bio Cybernetics / Technical Committee on Neurocomputing |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Changes in light response characteristics of mouse retinal ganglion cells depending on background light |
| Sub Title (in English) | |
| Keyword(1) | mouse retinal ganglion cell |
| Keyword(2) | step light stimulus |
| Keyword(3) | background light |
| Keyword(4) | mesopic and photopic vision |
| 1st Author's Name | Kenji Shiota |
| 1st Author's Affiliation | Osaka University(Osaka Univ.) |
| 2nd Author's Name | Yuki Naruto |
| 2nd Author's Affiliation | Osaka University(Osaka Univ.) |
| 3rd Author's Name | Yuki Kashiwagi |
| 3rd Author's Affiliation | Osaka University(Osaka Univ.) |
| 4th Author's Name | Naofumi Suemats |
| 4th Author's Affiliation | Osaka University(Osaka Univ.) |
| 5th Author's Name | Tetsuya Yagi |
| 5th Author's Affiliation | Osaka University(Osaka Univ.) |
| 6th Author's Name | Yuki Hayashida |
| 6th Author's Affiliation | Osaka University(Osaka Univ.) |
| Date | 2017-10-07 |
| Paper # | MBE2017-43 |
| Volume (vol) | vol.117 |
| Number (no) | MBE-230 |
| Page | pp.pp.11-16(MBE), |
| #Pages | 6 |
| Date of Issue | 2017-09-30 (MBE) |