| Presentation | 2017-06-27 Effect of focus scanning repetition frequency in high-intensity focused ultrasound exposure on sonochemical reaction Daisaku Mashiko, Shin-ya Nishitaka, Ryosuke Iwasaki, Maxime Lafond, Shin Yoshizawa, Shin-ichiro Umemura, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | High-intensity focused ultrasound (HIFU) permits on achieving energy deposition in a non-invasive manner. Such intense acoustic fields can induce temperature rise as well as acoustic cavitation. This last phenomenon is known to generate radical oxygen species (ROS), triggering the anti-cancer properties of sonosensitive substances. To optimize the generation of cavitation is a key point to reduce the HIFU exposure dose and consequently increase the safety of this method. In this particular study, a focus scanning technique is employed to widen the size of the cavitation cloud. The observations of the generated ROS via luminol reaction shows that this method does not maximize the volume exposed to ROS produced by cavitation. However, it is demonstrated that the timing of the sonication sequence plays a major role. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | HIFU / Sonodynamic Therapy / Cavitation Bubble |
| Paper # | US2017-25 |
| Date of Issue | 2017-06-20 (US) |
| Conference Information | |
| Committee | US |
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| Conference Date | 2017/6/27(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | Minoru Kurosawa(Tokyo Inst. of Tech.) |
| Vice Chair | Nobuyuki Endoh(KU) / Shinichi Takeuchi(Toin Univ. of Yokohama) |
| Secretary | Nobuyuki Endoh(Univ. of Toyama) / Shinichi Takeuchi(Univ. of Tokyo) |
| Assistant | Takenobu Tsuchiya(KU) |
| Paper Information | |
| Registration To | Technical Committee on Ultrasonics |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Effect of focus scanning repetition frequency in high-intensity focused ultrasound exposure on sonochemical reaction |
| Sub Title (in English) | |
| Keyword(1) | HIFU |
| Keyword(2) | Sonodynamic Therapy |
| Keyword(3) | Cavitation Bubble |
| 1st Author's Name | Daisaku Mashiko |
| 1st Author's Affiliation | Tohoku University(Tohoku Univ.) |
| 2nd Author's Name | Shin-ya Nishitaka |
| 2nd Author's Affiliation | Tohoku University(Tohoku Univ.) |
| 3rd Author's Name | Ryosuke Iwasaki |
| 3rd Author's Affiliation | Tohoku University(Tohoku Univ.) |
| 4th Author's Name | Maxime Lafond |
| 4th Author's Affiliation | Tohoku University(Tohoku Univ.) |
| 5th Author's Name | Shin Yoshizawa |
| 5th Author's Affiliation | Tohoku University(Tohoku Univ.) |
| 6th Author's Name | Shin-ichiro Umemura |
| 6th Author's Affiliation | Tohoku University(Tohoku Univ.) |
| Date | 2017-06-27 |
| Paper # | US2017-25 |
| Volume (vol) | vol.117 |
| Number (no) | US-111 |
| Page | pp.pp.25-30(US), |
| #Pages | 6 |
| Date of Issue | 2017-06-20 (US) |